AN INTEGRATED WORKFLOW FOR AUTOMATIC MAPPING OF DISULFIDE LINKAGES OF THERAPEUTIC PROTEINS USING HIGH-RESOLUTION LCMS, ETD FRAGMENTATION AND TARGETED INFORMATICS
Posters | 2015 | WatersInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesClinical Research
ManufacturerWaters
Key wordsdisulfide, bond, linkages, scrambled, unifi, mapping, bonds, etd, gcsf, peptides, therapeutic, mab, reporting, mse, proteins, expected, homodimer, workflow, bonded, intrachain, scrambling, quantitative, showing, interchain, alkylate, folding, encompasses, denature, list, protein, esi, comparison, processing, localization, induce, automated, mirror, backbone, glu, aspect, establishing, cleavage, analysis, trypsin, tracking, intra, assignment, inter, scientists, regions
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