Protein Confirmation Using the LC/MSD TOF and the Agilent TOF Protein Confirmation Software

Applications | 2004 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS
Industries
Proteomics
Manufacturer
Agilent Technologies
Key words
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Precise Characterization of IntactMonoclonal Antibodies by theAgilent 6545XT AdvanceBio LC/Q-TOFApplication NoteAuthorIntroductionDavid L. WongMonoclonal antibodies (mAbs) are a very important class of biopharmaceuticalmolecules. As a protein drug, thorough characterization of the mAb is required in eachof the manufacturing steps. Intact mAb...
Key words
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Application NotePROTEOMICSMETABOLOMICSGENOMICSINFORMATICSG LY I L E VA L C Y S G L U G L N ALASERLEUASPARGCYSVALLYSPROLY S P H E T Y R T H R L E U H I S LY SAccurate-Mass LC/TOF-MSfor Molecular Weight Confirmationof...
Key words
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Accurate Mass Measurement forIntact Proteins using ESI-oa-TOFApplication NoteDonghui Yi and Christine MillerAgilent TechnologiesJon D. Williams, GlaxoSmithKlineIntroductionMass spectrometry (MS) has become a corewith an orthogonal-acceleration reflectron time-technology for identification of primary proteinof-flight mass spectrometer (oa-TOF MS) for thestructure, and many combinations...
Key words
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Identification of Oxidation Sites ona Monoclonal Antibody Using anAgilent 1260 Infinity HPLC-Chip/MSSystem Coupled to an Accurate-Mass6520 Q-TOF LC/MSApplication NoteAuthorsAbstractRavindra GudihalAgilent Technologies India Pvt. Ltd.Bangalore, IndiaThe identification of oxidation sites on a monoclonal antibody (mAb) using anKeith WaddellAgilent Technologies, Inc.Santa Clara,...
Key words
mab, maboxidized, oxidizedoxidation, oxidationntlylq, ntlylqsslr, sslrpeptide, peptidetrypsin, trypsinmonoclonal, monoclonalmass, masstheoretical, theoreticalmsslr, msslrantibody, antibodybioconfirm, bioconfirmntlylqmsslr, ntlylqmsslrsequence