Characterization of mAb AggregationApplications | 2020 | Agilent Technologies InstrumentationGPC/SECIndustriesPharma & BiopharmaManufacturerAgilent TechnologiesKey wordsaggregate, aggregation, stressed, mab, freeze, thaw, samples, sec, aggregates, stress, formation, index, were, agilent, method, monomer, cycles, control, absorbance, contrasts, different, repeated, forms, log, subject, unstressed, menon, sreelakshmy, biosamples, thermomixer, exclusion, placed, antibody, thawing, sample, winuv, insets, nondestructive, rectangular, data, measurements, carried, area, quick, cuvette, xenon, thermal, pharmacy, presence, spectral
Similar PDF
Separate and Quantify Rituximab Aggregates and Fragments with High-Resolution SEC
2017|Agilent Technologies|Applications
Separate and Quantify RituximabAggregates and Fragments withHigh-Resolution SECThe Agilent 1260 Infinity Bio-Inert Quaternary LC Systemand the AdvanceBio SEC 300Å, 2.7 µm ColumnApplication NoteBiologics and BiosimilarsAuthorAbstractM.Sundaram PalaniswamyMonoclonal antibody aggregation can arise from multiple mechanisms, includingAgilent Technologies Pvt Ltdproduct and environmental factors....
Key words
innovator, innovatoraggregates, aggregatesbiosimilar, biosimilarrituximab, rituximabmau, mauintact, intactfragments, fragmentsstressed, stressedmabs, mabssec, secstress, stressadvancebio, advancebiomonomer, monomerarea, areaaggregation
High-throughput and Sensitive Size Exclusion Chromatography (SEC) of Biologics Using Agilent AdvanceBio SEC Columns
2017|Agilent Technologies|Applications
High-throughput and Sensitive SizeExclusion Chromatography (SEC) ofBiologics Using Agilent AdvanceBioSEC ColumnsAgilent AdvanceBio SEC 300 Å, 2.7 µm columnsApplication noteBio-PharmaceuticalAuthorAbstractM. Sundaram PalaniswamyMonoclonal antibody (mAb) aggregation can arise due to multiple mechanismsAgilent Technologies Inc.during cell culture, harvest, purification, storage, and filling. Size...
Key words
adc, adcherceptin, herceptinmau, mauadvancebio, advancebiosec, secmonomer, monomeraggregate, aggregatemab, mabaggregates, aggregatesoverlay, overlayreplicates, replicatesstressed, stresseddegraded, degradedpreservative, preservativecolumns
T he Analysis of Multimeric Monoclonal Antibody Aggregates by Size-Exclusion UPLC
2013|Waters|Applications
The Analysis of Multimeric Monoclonal Antibody Aggregatesby Size-Exclusion UPLCStephan Koza, Matthew Lauber, and Kenneth J. FountainWaters Corporation, Milford, MA, USAA P P L I C AT I O N B E N E F I T S■■ACQUITY UPLC SEC Technology...
Key words
multimeric, multimericdimer, dimermultimers, multimersaggregates, aggregatesuplc, uplctrimer, trimerexclusion, exclusionmonoclonal, monoclonalmonomer, monomerdimeric, dimericsize, sizemab, mabantibody, antibodyaggregate, aggregateforms
Agilent Biocolumns - Aggregate/Fragment Analysis - Application Compendium
2021|Agilent Technologies|Guides
Agilent BiocolumnsAggregate/Fragment AnalysisApplication Compendium ContentsBackground2Getting Started3How to Guide - Size Exclusion Chromatography for BiomoleculeAnalysis - 5991-3651EN 4Featured Application NotesElevate Your mAb Aggregate Analysis - 5994-2709EN12222High-Resolution, High-Throughput Size Exclusion ChromatographyAnalysis of Monoclonal Antibodies - 5994-0828EN29Sensitive Native Mass Spectrometry of MacromoleculesUsing Standard Flow LC/MS...
Key words
return, returnsection, sectioncontents, contentsmau, mausec, secinsulin, insulinmin, minsize, sizeprotein, proteinmonomer, monomeradvancebio, advancebiotime, timeexclusion, exclusionaggregates, aggregatesaggregate