Lipid Nanoparticle Compositional Analysis Using Charged Surface Hybrid Phenyl-Hexyl Separation With Evaporative Light Scattering DetectionApplications | 2021 | WatersInstrumentation
HPLC
Industries
Lipidomics
Manufacturer
Waters
Key words

 

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Application NoteRapid Analysis of Lipid NanoparticleComponents Using BioAccord LC-MS SystemGiorgis Isaac, Nilini Ranbaduge, Bonnie A. Alden, Colette Quinn, Weibin Chen, Robert S. PlumbWaters CorporationAbstractThe recent success of mRNA vaccines for COVID-19 is in part due to the development of lipid...
Key words
lipid, lipidbioaccord, bioaccordlnp, lnpnanoparticle, nanoparticleunifi, unifilnps, lnpscompare, compareclasses, classesdeliver, deliverfactorial, factorialimpurities, impuritiesunknown, unknownspecies, speciesfunction, functionmrna
Application NoteModernized Impurity Analysis of the KinaseInhibitor Imatinib by High-Resolution LCWith MS-Compatible Mobile PhasesPeng Chen, Bonnie A. Alden, Matthew A. LauberWaters CorporationAbstract A UPLC method has been developed with a charged surface phenyl stationary phase for the separation of imatiniband its...
Key words
imatinib, imatinibuplc, uplcphenyl, phenylhexyl, hexylkinase, kinasevion, vioncsh, cshims, imsphases, phasesnine, nineqtof, qtofmolecular, molecularseparation, separationcorroborate, corroborateimpurity
LIPID NANOPARTICLES—GET TO KNOW THEM ANALYTICALLYGiorgis Isaac; Nilini Ranbaduge; Bonnie Alden; Colette Quinn; Weibin ChenWaters Corporation, Milford, MA 01757INTRODUCTIONLipid Nanoparticles (LNPs)The recent success of mRNA vaccines is largely due to their abilityto use human ribosomes to produce the correct protein....
Key words
lipid, lipidlipids, lipidsnanoparticles, nanoparticlescomplex, complexpivot, pivotdspc, dspcspectroscopically, spectroscopicallybonnie, bonniecolette, colettegiorgis, giorgisisaac, isaaclnps, lnpsquinn, quinnlnp, lnpbinary
Rapid Analysis of Lipid Nanoparticle Components Using BioAccord™ LC-MS SystemGiorgis Isaac, Nilini Ranbaduge, Colette Quinn, Weibin Chen and Robert S. PlumbWaters Corporation, Milford, MAIntroduction▪ The recent success of mRNA vaccines in SARSCoV-2 clinical trials is in part due to thedevelopment...
Key words
lnp, lnplipid, lipidnanoparticle, nanoparticledspc, dspcbioaccord, bioaccordmrna, mrnaspectroscopically, spectroscopicallybinary, binarydelivery, deliverycomponents, componentspegylated, pegylatedattack, attacksilent, silentanalysis, analysisacquity

Lipid Nanoparticle Compositional Analysis Using Charged Surface Hybrid Phenyl-Hexyl Separation With Evaporative Light Scattering DetectionApplications | 2021 | WatersInstrumentation
HPLC
Industries
Lipidomics
Manufacturer
Waters
Key words

 

Similar PDF

Toggle
Application NoteRapid Analysis of Lipid NanoparticleComponents Using BioAccord LC-MS SystemGiorgis Isaac, Nilini Ranbaduge, Bonnie A. Alden, Colette Quinn, Weibin Chen, Robert S. PlumbWaters CorporationAbstractThe recent success of mRNA vaccines for COVID-19 is in part due to the development of lipid...
Key words
lipid, lipidbioaccord, bioaccordlnp, lnpnanoparticle, nanoparticleunifi, unifilnps, lnpscompare, compareclasses, classesdeliver, deliverfactorial, factorialimpurities, impuritiesunknown, unknownspecies, speciesfunction, functionmrna
Application NoteModernized Impurity Analysis of the KinaseInhibitor Imatinib by High-Resolution LCWith MS-Compatible Mobile PhasesPeng Chen, Bonnie A. Alden, Matthew A. LauberWaters CorporationAbstract A UPLC method has been developed with a charged surface phenyl stationary phase for the separation of imatiniband its...
Key words
imatinib, imatinibuplc, uplcphenyl, phenylhexyl, hexylkinase, kinasevion, vioncsh, cshims, imsphases, phasesnine, nineqtof, qtofmolecular, molecularseparation, separationcorroborate, corroborateimpurity
LIPID NANOPARTICLES—GET TO KNOW THEM ANALYTICALLYGiorgis Isaac; Nilini Ranbaduge; Bonnie Alden; Colette Quinn; Weibin ChenWaters Corporation, Milford, MA 01757INTRODUCTIONLipid Nanoparticles (LNPs)The recent success of mRNA vaccines is largely due to their abilityto use human ribosomes to produce the correct protein....
Key words
lipid, lipidlipids, lipidsnanoparticles, nanoparticlescomplex, complexpivot, pivotdspc, dspcspectroscopically, spectroscopicallybonnie, bonniecolette, colettegiorgis, giorgisisaac, isaaclnps, lnpsquinn, quinnlnp, lnpbinary
Rapid Analysis of Lipid Nanoparticle Components Using BioAccord™ LC-MS SystemGiorgis Isaac, Nilini Ranbaduge, Colette Quinn, Weibin Chen and Robert S. PlumbWaters Corporation, Milford, MAIntroduction▪ The recent success of mRNA vaccines in SARSCoV-2 clinical trials is in part due to thedevelopment...
Key words
lnp, lnplipid, lipidnanoparticle, nanoparticledspc, dspcbioaccord, bioaccordmrna, mrnaspectroscopically, spectroscopicallybinary, binarydelivery, deliverycomponents, componentspegylated, pegylatedattack, attacksilent, silentanalysis, analysisacquity
 

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