ASMS 2021: Lipid Separation and Structural Characterization Using Travelling Wave Cyclic Ion Mobility

Posters | 2021 | WatersInstrumentation
Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Industries
Lipidomics
Manufacturer
Waters
Key words
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ANALYSIS OF LIPID SIGNALING CLASS ANALYTES USING A TRAVELLING WAVE CYCLIC ION MOBILITY SEPARATORMichael McCullagh1, Martin Palmer1, Steven Keller1, David Heywood1, James I Langridge1 and Johannes PC Vissers1Waters Corporation, Wilmslow, United KingdomINTRODUCTIONLipid signaling analytes represent a diverse group of biomoleculesthat...
Key words
cyclic, cycliccid, ciddouble, doublebond, bondims, imssignaling, signalingisomeric, isomericcim, cimcircles, circleslipid, lipidseparator, separatorresolution, resolutionfragmentation, fragmentationwere, wereobtained
Lipid Separation and Structural Characterization Using Hybrid Surface Technologyand Travelling Wave Cyclic Ion MobilityGiorgis Isaac, Nyasha Munjoma, Martin Palmer, Lee A. Gethings, Robert S. Plumb1 Waters CorporationINTRODUCTIONRESULTSRESULTS• The analysis and structural characterization of lipidsremain challenging due to the chemical structurediversity...
Key words
mobility, mobilityseparation, separationstructural, structuralcyclic, cycliccharacterization, characterizationion, ioncirculate, circulatewaves, wavescim, cimslice, slicetravelling, travellingactivation, activationwave, wavepresentation, presentationbiomolecules
Lipid Isomer Separation Using Travelling Wave Cyclic Ion Mobility Mass SpectrometryGiorgis Isaac, Hernando Olivos, and Robert S. Plumb; Waters Corporation, Milford, MAIntroductionResultsResults▪ Galactosylceramide (GalCer) and glucosylceramide(GlcCer) are isomers and only differ in the positionof the hydroxy group at the C-4...
Key words
isomers, isomersgalcer, galcerglccer, glccermobility, mobilitycyclic, cycliclipid, lipidisomer, isomergalactosylceramide, galactosylceramideganglioside, gangliosideglucosylceramide, glucosylceramideceramides, ceramidesavanti, avantiprofound, profoundseparation, separationtravelling
Application NoteBiopharma/PharmaMinimizing the Interaction ofPhospholipids with LC HardwarePhospholipid analysis using the Agilent 1290 Infinity IIBio LC System and Agilent InfinityLab LC/MSD iQAuthorsGerd Vanhoenacker,Ruben t’Kindt, Pat Sandra, andKoen SandraRIC groupPresident Kennedypark 26,B-8500 Kortrijk, BelgiumSonja Schneider andUdo HuberAgilent Technologies, Inc.AbstractPhospholipids are an...
Key words
sst, sstlpa, lpapip, pippeek, peekbio, bioinfinitylab, infinitylabphospholipids, phospholipidscolumn, columnphosphatidylinositol, phosphatidylinositolmsd, msdstainless, stainlesslined, linedsteel, steeladsorption, adsorptionthermostat