ASMS 2021: Rapid Analysis of Synthetic mRNA Cap Structure using Ion Pairing Reversed Phase Liquid Chromatography coupled to Mass SpectrometryPosters | 2021 | WatersInstrumentationHPLC, LC/MSIndustriesPharma & BiopharmaManufacturerWatersKey wordssynthetic, oligonucleotides, probe, mrna, fifth, rnase, surface, capping, uhplc, coupled, heavily, rna, marked, pairing, dispersion, detecting, when, hybrid, improvements, influence, applicable, using, inert, representative, sequence, choice, down, impurities, analyzing, conventional, related, injections, system, can, analyses, less, rapid, sensitive, containing, column, achieved, from, first, recovery, highly, same, obtained, than, quality, performed
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[ APPLICATION NOTEBOOK ]APPLICATION SOLUTIONS FOROLIGONUCLEOTIDESTable of ContentsIntroduction – UPLC Analysis of Synthetic Oligonucleotides......................................................................................................................... 4[ HPLC & UPLC Separations ]Real-Time Analysis of RNAi Duplexes ....................................................................................................................................................................... 8Semi-Preparative Scale Single-Stranded RNA Purification .......................................................................................................................... 11Oligonucleotide Separation Technology: Synthesis Challenges and HPLC Isolation Options...
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Rapid Analysis of Synthetic mRNA Cap Structure Using Ion-Pairing RPLC with the BioAccord LC-MS System
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