ASMS 2021: DESITM Cyclic IMS Enables the Detection and Spatial Distribution of Proteins in Tuberculosis Granulomas | LabRulez LCMS
 

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25YEARSMALDIIntegrating Ultra-High Speed MALDI-TOF andMALDI MRMS Imaging For Spatial ProteomicsMALDI imaging is a powerful technology that allows the detection of analytes fromtissue while preserving their spatial distributionIntroductionCystic fibrosis (CF) is inherited inan autosomal recessive manner,and caused by the presence ofmutations...
Key words
maldi, maldiimaging, imagingmrms, mrmsspatial, spatialtissue, tissuetof, tofcalcyclin, calcyclinfibrosis, fibrosiscystic, cystichtx, htxultra, ultrasolarix, solarixspeed, speedhemoglobin, hemoglobinhigh
ADVANTAGES OF HIGH RESOLUTION ION MOBILITY ON THE CYCLIC IMS FOR DESI MASS SPECTROMETRY IMAGING1Susan Slade, 1Emmanuelle Claude.1Waters Corporation, Wilmslow, UK.INTRODUCTIONRESULTSTMDesorption DESI is a powerful andsensitive MS ionisation technique for theprofiling and imaging of metabolites andlipids direct from unmodified complexbiological...
Key words
desi, desimobility, mobilityimaging, imagingpass, passcyclic, cyclicims, imsion, ionseparation, separationmulti, multiisobaric, isobaricsprayer, sprayerporcine, porcinewhere, wherepasses, passesliver
BENEFITS OF HIGH RESOLUTION ION MOBILITY SEPARATION ON THE CYCLIC IMS FORDESI MASS SPECTROMETRY IMAGING1SusanSlade, 1Emmanuelle Claude; 1Waters Corporation, Wilmslow, UKResultsIntroductiona)Desorption DESITM is a powerful and sensitive MSionisation technique for the profiling and imaging ofmetabolites and lipids direct from unmodified...
Key words
desi, desiimaging, imagingcyclic, cyclicims, imsmobility, mobilityseparation, separationpasses, passesion, ionisobaric, isobariccyclictm, cyclictmseriestm, seriestmdesitm, desitmpass, passdevice, devicetravelling
SPATIAL DISTRIBUTION AND IDENTIFICATION OF PROTEIN INTUBERCULOSIS GRANULOMAS USING DESI AND CYCLIC ION MOBILITYHernando Olivos1, Emmanuelle Claude1, Véronique Dartois2,3 and Claire L. Carter2,41Waters Corporation, Milford, MA 2 Center for Discovery and Innovation, Hackensack Meridian Health Nutley, NJ 3 Department of...
Key words
granulomas, granulomasimages, imagesprotein, proteinlesion, lesiongranuloma, granulomahba, hbanecrotic, necroticregions, regionsmacrophages, macrophageshbb, hbbtuberculosis, tuberculosisproteins, proteinspreclinical, preclinicalinform, informmerged
 

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25YEARSMALDIIntegrating Ultra-High Speed MALDI-TOF andMALDI MRMS Imaging For Spatial ProteomicsMALDI imaging is a powerful technology that allows the detection of analytes fromtissue while preserving their spatial distributionIntroductionCystic fibrosis (CF) is inherited inan autosomal recessive manner,and caused by the presence ofmutations...
Key words
maldi, maldiimaging, imagingmrms, mrmsspatial, spatialtissue, tissuetof, tofcalcyclin, calcyclinfibrosis, fibrosiscystic, cystichtx, htxultra, ultrasolarix, solarixspeed, speedhemoglobin, hemoglobinhigh
ADVANTAGES OF HIGH RESOLUTION ION MOBILITY ON THE CYCLIC IMS FOR DESI MASS SPECTROMETRY IMAGING1Susan Slade, 1Emmanuelle Claude.1Waters Corporation, Wilmslow, UK.INTRODUCTIONRESULTSTMDesorption DESI is a powerful andsensitive MS ionisation technique for theprofiling and imaging of metabolites andlipids direct from unmodified complexbiological...
Key words
desi, desimobility, mobilityimaging, imagingpass, passcyclic, cyclicims, imsion, ionseparation, separationmulti, multiisobaric, isobaricsprayer, sprayerporcine, porcinewhere, wherepasses, passesliver
BENEFITS OF HIGH RESOLUTION ION MOBILITY SEPARATION ON THE CYCLIC IMS FORDESI MASS SPECTROMETRY IMAGING1SusanSlade, 1Emmanuelle Claude; 1Waters Corporation, Wilmslow, UKResultsIntroductiona)Desorption DESITM is a powerful and sensitive MSionisation technique for the profiling and imaging ofmetabolites and lipids direct from unmodified...
Key words
desi, desiimaging, imagingcyclic, cyclicims, imsmobility, mobilityseparation, separationpasses, passesion, ionisobaric, isobariccyclictm, cyclictmseriestm, seriestmdesitm, desitmpass, passdevice, devicetravelling
SPATIAL DISTRIBUTION AND IDENTIFICATION OF PROTEIN INTUBERCULOSIS GRANULOMAS USING DESI AND CYCLIC ION MOBILITYHernando Olivos1, Emmanuelle Claude1, Véronique Dartois2,3 and Claire L. Carter2,41Waters Corporation, Milford, MA 2 Center for Discovery and Innovation, Hackensack Meridian Health Nutley, NJ 3 Department of...
Key words
granulomas, granulomasimages, imagesprotein, proteinlesion, lesiongranuloma, granulomahba, hbanecrotic, necroticregions, regionsmacrophages, macrophageshbb, hbbtuberculosis, tuberculosisproteins, proteinspreclinical, preclinicalinform, informmerged
 

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