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SOLA solid-phase extraction (SPE)method development guideMethod optimization for SPE bioanalysis IntroductionSolid-phase extraction (SPE) is said to be the most effective techniquein modern bioanalysis with regard to isolation of analytes of interestfrom complex biological matrices. It improves accuracy, precision,allows for much lower...
Key words
spe, spesola, solawash, washhrp, hrpsolaµ, solaµneutral, neutralanalyte, analyteexchange, exchangesax, saxwax, waxload, loadwcx, wcxscx, scxelution, elutionsample
APPLICATION NOTEJon Bardsley, Joanne Jones,Thermo Fisher Scientific, Runcorn, UKKey wordsSPE, SOLA, SOLAμ, SCX, Hypersil GOLD aQ, opiatesGoalTo describe a reproducible optimization procedurefor the isolation of opioids from human urineutilizing solid phase extraction (SPE). Subsequentanalysis was carried out with liquid chromatographyseparation...
Key words
spe, spescientific, scientificsola, solathermo, thermomicro, microsolaμ, solaμscx, scxdilute, dilutemanifold, manifoldsample, samplescale, scaleextract, extractextraction, extractiongrade, gradeelution
APPLICATION NOTEJon Bardsley, Joanne Jones,Thermo Fisher Scientific, Runcorn, UKKey wordsSPE, SOLA, SOLAμ, SCX, Hypersil GOLD aQ, opiatesGoalTo describe a reproducible optimization procedurefor the isolation of opioids from human urineutilizing solid phase extraction (SPE). Subsequentanalysis was carried out with liquid chromatographyseparation...
Key words
spe, spescientific, scientificsola, solamicro, microthermo, thermosolaμ, solaμscx, scxdilute, dilutemanifold, manifoldsample, samplescale, scaleextract, extractextraction, extractiongrade, gradeelution
Jon Bardsley, Thermo Fisher Scientific, Runcorn, UKKey WordsSteroid hormones, steroids, SOLA, SOLAµ HRP, reversed phase SPE,LC-MS/MS, Syncronis C18, micro-scale SPE, testosterone,androstenedione, 17-hydroxy progesteroneGoalTo describe an accurate and precise high-throughput analytical techniquefor the analysis of testosterone, androstenedione, and 17-hydroxyprogesterone utilizing micro-scale...
Key words
androstenedione, androstenedionetestosterone, testosteronenominal, nominalpbs, pbsplasma, plasmamatrix, matrixsurrogate, surrogatebias, biasendogenous, endogenousfrom, fromlevels, levelslow, lowsaline, salinehigh, highconcentration
 

Similar PDF

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SOLA solid-phase extraction (SPE)method development guideMethod optimization for SPE bioanalysis IntroductionSolid-phase extraction (SPE) is said to be the most effective techniquein modern bioanalysis with regard to isolation of analytes of interestfrom complex biological matrices. It improves accuracy, precision,allows for much lower...
Key words
spe, spesola, solawash, washhrp, hrpsolaµ, solaµneutral, neutralanalyte, analyteexchange, exchangesax, saxwax, waxload, loadwcx, wcxscx, scxelution, elutionsample
APPLICATION NOTEJon Bardsley, Joanne Jones,Thermo Fisher Scientific, Runcorn, UKKey wordsSPE, SOLA, SOLAμ, SCX, Hypersil GOLD aQ, opiatesGoalTo describe a reproducible optimization procedurefor the isolation of opioids from human urineutilizing solid phase extraction (SPE). Subsequentanalysis was carried out with liquid chromatographyseparation...
Key words
spe, spescientific, scientificsola, solathermo, thermomicro, microsolaμ, solaμscx, scxdilute, dilutemanifold, manifoldsample, samplescale, scaleextract, extractextraction, extractiongrade, gradeelution
APPLICATION NOTEJon Bardsley, Joanne Jones,Thermo Fisher Scientific, Runcorn, UKKey wordsSPE, SOLA, SOLAμ, SCX, Hypersil GOLD aQ, opiatesGoalTo describe a reproducible optimization procedurefor the isolation of opioids from human urineutilizing solid phase extraction (SPE). Subsequentanalysis was carried out with liquid chromatographyseparation...
Key words
spe, spescientific, scientificsola, solamicro, microthermo, thermosolaμ, solaμscx, scxdilute, dilutemanifold, manifoldsample, samplescale, scaleextract, extractextraction, extractiongrade, gradeelution
Jon Bardsley, Thermo Fisher Scientific, Runcorn, UKKey WordsSteroid hormones, steroids, SOLA, SOLAµ HRP, reversed phase SPE,LC-MS/MS, Syncronis C18, micro-scale SPE, testosterone,androstenedione, 17-hydroxy progesteroneGoalTo describe an accurate and precise high-throughput analytical techniquefor the analysis of testosterone, androstenedione, and 17-hydroxyprogesterone utilizing micro-scale...
Key words
androstenedione, androstenedionetestosterone, testosteronenominal, nominalpbs, pbsplasma, plasmamatrix, matrixsurrogate, surrogatebias, biasendogenous, endogenousfrom, fromlevels, levelslow, lowsaline, salinehigh, highconcentration
 

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