Similar PDF

Toggle
Developing the analytics and analytical workflows supporting the analysisof the next generation of biotherapeutic and gene therapies.Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D.Waters Lunch SeminarTuesday January 28, 2020WCBP 2020DiamondProgram Partner©2020 Waters Corporation. COMPANY CONFIDENTIAL1 Ralph Waldo Emersonb. 1803 - d.1882©2020...
Key words
capsid, capsidaav, aavempty, emptydevelopment, developmentgene, geneprotein, proteincapsids, capsidstherapy, therapyproteins, proteinsiex, iexmeasure, measurefull, fullrplc, rplcmonitoring, monitoringcharacterization
COMPLIANT-READY WORKFLOW FOR MASS CONFIRMATION OF OLIGONUCLEOTIDES AND RELATED IMPURITIESAndy Tudor, Maria Basanta-Sanchez, Joe Fredette, Brooke Koshel, Jonathan Fox, Barry Dyson, Alessio Zammataro, Laetitia Denbigh, Barbara Sullivan, Weibin Chen and Keith RichardsonWaters Corporation, Milford, MAMETHODSOVERVIEWWaters UNIFI™ Scientific Information System is...
Key words
oligonucleotide, oligonucleotideworkflow, workflowunifi, unifimass, massoligonucleotides, oligonucleotidesoligos, oligosrda, rdaimpurities, impuritiesconfirmation, confirmationinformatics, informaticsrelated, relatedcomplianceready, compliancereadyimprovements, improvementsresurgence, resurgenceost
Application NoteIntact Mass Confirmation Analysis on theBioAccord LC-MS System for a Variety ofExtensively Modified OligonucleotidesCatalin E. Doneanu, Jonathan Fox, Emma Harry, Chris Knowles, Ying Qing Yu, JosephFredette, Weibin ChenWaters CorporationFor research use only. Not for use indiagnostic procedures. AbstractThis application note...
Key words
oligonucleotides, oligonucleotidesmodified, modifiedoligonucleotide, oligonucleotideunmodified, unmodifiedisotopic, isotopicdeconvolution, deconvolutionbioaccord, bioaccordmodel, modelheavily, heavilyextensively, extensivelyppt, pptmodifications, modificationsoligo, oligosection, sectioncompliance
[ APPLICATION NOTEBOOK ]APPLICATION SOLUTIONS FOROLIGONUCLEOTIDES Table of ContentsIntroduction – UPLC Analysis of Synthetic Oligonucleotides......................................................................................................................... 4[ HPLC & UPLC Separations ]Real-Time Analysis of RNAi Duplexes ....................................................................................................................................................................... 8Semi-Preparative Scale Single-Stranded RNA Purification .......................................................................................................................... 11Oligonucleotide Separation Technology: Synthesis Challenges and HPLC Isolation Options...
Key words
oligonucleotides, oligonucleotidesoligonucleotide, oligonucleotideuplc, uplcacquity, acquityrnai, rnaiost, ostduplex, duplexpromass, promassduplexes, duplexessirna, sirnawaters, watersqda, qdarna, rnaanalysis, analysispairing
 

Similar PDF

Toggle
Developing the analytics and analytical workflows supporting the analysisof the next generation of biotherapeutic and gene therapies.Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D.Waters Lunch SeminarTuesday January 28, 2020WCBP 2020DiamondProgram Partner©2020 Waters Corporation. COMPANY CONFIDENTIAL1 Ralph Waldo Emersonb. 1803 - d.1882©2020...
Key words
capsid, capsidaav, aavempty, emptydevelopment, developmentgene, geneprotein, proteincapsids, capsidstherapy, therapyproteins, proteinsiex, iexmeasure, measurefull, fullrplc, rplcmonitoring, monitoringcharacterization
COMPLIANT-READY WORKFLOW FOR MASS CONFIRMATION OF OLIGONUCLEOTIDES AND RELATED IMPURITIESAndy Tudor, Maria Basanta-Sanchez, Joe Fredette, Brooke Koshel, Jonathan Fox, Barry Dyson, Alessio Zammataro, Laetitia Denbigh, Barbara Sullivan, Weibin Chen and Keith RichardsonWaters Corporation, Milford, MAMETHODSOVERVIEWWaters UNIFI™ Scientific Information System is...
Key words
oligonucleotide, oligonucleotideworkflow, workflowunifi, unifimass, massoligonucleotides, oligonucleotidesoligos, oligosrda, rdaimpurities, impuritiesconfirmation, confirmationinformatics, informaticsrelated, relatedcomplianceready, compliancereadyimprovements, improvementsresurgence, resurgenceost
Application NoteIntact Mass Confirmation Analysis on theBioAccord LC-MS System for a Variety ofExtensively Modified OligonucleotidesCatalin E. Doneanu, Jonathan Fox, Emma Harry, Chris Knowles, Ying Qing Yu, JosephFredette, Weibin ChenWaters CorporationFor research use only. Not for use indiagnostic procedures. AbstractThis application note...
Key words
oligonucleotides, oligonucleotidesmodified, modifiedoligonucleotide, oligonucleotideunmodified, unmodifiedisotopic, isotopicdeconvolution, deconvolutionbioaccord, bioaccordmodel, modelheavily, heavilyextensively, extensivelyppt, pptmodifications, modificationsoligo, oligosection, sectioncompliance
[ APPLICATION NOTEBOOK ]APPLICATION SOLUTIONS FOROLIGONUCLEOTIDES Table of ContentsIntroduction – UPLC Analysis of Synthetic Oligonucleotides......................................................................................................................... 4[ HPLC & UPLC Separations ]Real-Time Analysis of RNAi Duplexes ....................................................................................................................................................................... 8Semi-Preparative Scale Single-Stranded RNA Purification .......................................................................................................................... 11Oligonucleotide Separation Technology: Synthesis Challenges and HPLC Isolation Options...
Key words
oligonucleotides, oligonucleotidesoligonucleotide, oligonucleotideuplc, uplcacquity, acquityrnai, rnaiost, ostduplex, duplexpromass, promassduplexes, duplexessirna, sirnawaters, watersqda, qdarna, rnaanalysis, analysispairing
 

Related content

Evaluating the Waters ACQUITY Premier System as a Flexible LC Platform That Can Be Broadly Deployed in Biopharmaceutical Labs

Applications
| 2021 | Waters
Instrumentation
HPLC, GPC/SEC
Manufacturer
Waters
Industries
Pharma & Biopharma

Analysis of 510 Pesticide Residues in Honey and Onion on an Agilent 6470 Triple Quadrupole LC/MS System

Applications
| 2021 | Agilent Technologies
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Food & Agriculture

Rapid Detection of Illicit Drugs and Psychoactive Plant Component by Green Technology DPiMSTM-8060

Applications
| 2021 | Shimadzu
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ, DART
Manufacturer
Shimadzu
Industries
Forensics
 

Related content

Evaluating the Waters ACQUITY Premier System as a Flexible LC Platform That Can Be Broadly Deployed in Biopharmaceutical Labs

Applications
| 2021 | Waters
Instrumentation
HPLC, GPC/SEC
Manufacturer
Waters
Industries
Pharma & Biopharma

Analysis of 510 Pesticide Residues in Honey and Onion on an Agilent 6470 Triple Quadrupole LC/MS System

Applications
| 2021 | Agilent Technologies
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Food & Agriculture

Rapid Detection of Illicit Drugs and Psychoactive Plant Component by Green Technology DPiMSTM-8060

Applications
| 2021 | Shimadzu
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ, DART
Manufacturer
Shimadzu
Industries
Forensics
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use

LabRulez s.r.o., all rights reserved.