Seamless Method Transfer to the Agilent 1290 Infinity II Bio LC System

Technical notes | 2020 | Agilent TechnologiesInstrumentation
HPLC
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
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Application NoteBiopharmaRobust and Reliable Peptide MappingThe Agilent 1290 Infinity II Bio LC System as the newplatform for UV and MS-based primary structure andPTMs analysis of mAbsResponse (mAU)40UV3020100×1078MSTIC (counts)64200102030Retention time (min)AuthorAndré FeithAgilent Technologies, Inc.AbstractPeptide mapping is the gold standard for elucidating...
Key words
mapping, mappingpeptide, peptideprimary, primarystructure, structureadvancebio, advancebioretention, retentionmethod, methodagilent, agilentmin, minmau, maurrhd, rrhddeamidation, deamidationptms, ptmstime, timersd
Agilent BioHPLC ColumnsCharacterization of NIST MonoclonalAntibody Critical Quality AttributesApplication Compendium ContentsAgilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted fromNISTmAb RM 8671 batch. Quality control (QC) testing is performed usingAgilent LC-MS system. QC batch release test includes aggregate profile, chargevariants and intact mass...
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mab, mabglycan, glycanadvancebio, advancebiocounts, countsmapping, mappingpeptide, peptideagilent, agilentmonoclonal, monoclonalglycans, glycansmin, mincolumn, columnmass, massprotein, proteinnistmab, nistmabassaymap
Agilent InfinityLab Bio LC SolutionsHigh-PerformanceBiopharma AnalysisApplication compendium 2 Overcome AnalyticalChallenges in BiopharmaThe growing complexity of biopharma analysis calls for innovationthat delivers excellence across the biopharmaceutical workflow.The Agilent InfinityLab Bio LC Solutions comprise a full range ofentirely biocompatible and bio-inert LC systems that...
Key words
retention, retentionbio, biogradient, gradientmin, mintime, timenistmab, nistmabresponse, responsemau, maupeptide, peptidemapping, mappingcharge, chargeagilent, agilentmab, mabrsd, rsdantibody
Analyzing Raw Material for Oligonucleotide Synthesis
2021|Agilent Technologies|Applications
Application NoteBiopharma/PharmaAnalyzing Raw Material forOligonucleotide SynthesisFlexible and robust method development for theanalysis of nucleoside phosphoramidites with theAgilent 1290 Infinity II Bio LC System100Response (mAU)80604020005101520Time (min)AuthorAndré FeithAgilent Technologies, Inc.AbstractAs the first step of the biopharmaceutical production process, the raw materialof any...
Key words
phosphoramidites, phosphoramiditessynthesis, synthesisphosphoramidite, phosphoramiditedna, dnatime, timeretention, retentionbio, bioraw, rawvwd, vwdmaterial, materialproduct, productoligonucleotide, oligonucleotidedevelopment, developmentflow, flowmau