<p><strong>We are pleased to invite you to our upcoming free online webinar on June 11, 2026 focused on one of the most pressing challenges in environmental monitoring and water quality management — PFAS (Per- and Polyfluoroalkyl Substances).</strong></p><p>As regulatory frameworks continue to evolve and compliance deadlines approach, laboratories, water utilities, and environmental professionals need robust, reliable, and cutting-edge analytical solutions to stay ahead.</p><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://events.teams.microsoft.com/event/91d97003-fe33-4dca-b80b-160d9f8a5655@485ca04e-6f74-4050-9764-cdb4bfa89c25"><strong>Registration HERE</strong></a></p></blockquote><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/ALS_analyzy_PFAS_a9e4a87fbc.jpg" alt="ALS: Advanced PFAS Analytical Services " srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_ALS_analyzy_PFAS_a9e4a87fbc.jpg 245w," sizes="100vw" width="600" height="336"></p><h4><strong>🎤 Our Speaker</strong></h4><p>The webinar will be hosted by <strong>Jana Kováčová, Ph.D., PFAS Regional Lead for Continental Europe Environmental Division</strong>, who has dedicated the last several years to the field of PFAS analysis and determination in ALS laboratories. Jana is a recognized expert in PFAS environmental analytics and will share practical insights and the latest developments in analytical strategies to help your organization achieve and maintain compliance.</p><h4><strong>🎯 What You Will Learn</strong></h4><ul><li>Latest <strong>regulatory developments</strong> and compliance requirements for PFAS in water, including <strong>EU Drinking Water Directive 2020/2184</strong> and its implications for water suppliers and laboratories.</li><li><strong>Regulatory updates for surface water and groundwater</strong> — what's new and what to expect next.</li><li>Overview of <strong>advanced analytical strategies</strong> for PFAS detection and quantification in water matrices and how we analyse PFAS samples.</li><li>Key <strong>analytical challenges</strong> associated with PFAS testing — from ultra-trace detection to matrix interferences and contamination control.</li><li>The critical importance of using tested <strong>sampling containers</strong> and sample preservation to ensure reliable results.</li><li>Illustrative <strong>examples of results</strong> from real-world PFAS water analyses.</li><li>How ALS can support your needs with <strong>accredited PFAS testing services</strong>.</li></ul><h4><strong>👥 Who Should Attend</strong></h4><p>This webinar is designed for our clients, professionals, laboratory and technical staff, scientists, as well as anyone with an interest in analytical chemistry who wants to better understand the occurrence of these "forever chemicals" in the environment. &nbsp;</p><h4><strong>💬 Q&amp;A Session</strong></h4><p>There will be a live Q&amp;A session at the end of the webinar. You are welcome to submit your questions in advance during registration or ask them live on the day.</p><h4><strong>📅 Additional Webinar Info:</strong></h4><ul><li><strong>Platform: </strong>Microsoft Teams (online)</li><li><strong>Time: </strong>10:00 CEST</li><li><strong>Language: </strong>English</li><li><strong>Duration:</strong> approx. 45 - 60 minutes (incl. Q&amp;A)<br>Extras: If you are unable to attend on the day, please register and we will provide you with the recording of the webinar.</li></ul><h4><strong>🔬 About ALS Environmental</strong></h4><p>ALS is a global leader in environmental testing and analytical services, providing accredited PFAS analysis to clients across Europe and beyond. Our dedicated PFAS experts help clients navigate the complex regulatory landscape with confidence.</p><blockquote><p>For further information, please contact us on: <strong>marketing.cz@alsglobal.com</strong></p></blockquote><p>We look forward to welcoming you to this important discussion on PFAS compliance in water.</p>

Invitation to the ALS Webinar PFAS in Water 2026: Achieving Compliance through Advanced Analytical Strategies

<p><strong>Why are switchable 2D-LC workflows fit for mAb manufacturing? Discover a practical AQbD approach for monitoring charge and size variants in one hour.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_689c6925a2.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_689c6925a2.jpeg 245w," sizes="100vw" width="1024" height="512"></p><p><strong>Lost material. Delayed production timelines. Reworks across teams.</strong></p><p>If you’re working with monoclonal antibodies (mAbs) or other biopharmaceuticals, you already know the challenge: biological reactions are variable.</p><p>Unlike traditional small-molecule drugs, with simpler and more predictable chemical structures, biotherapeutics exist in a dynamic state of microheterogeneity — no two batches are ever truly identical.</p><p>Whether undergoing production, processing, or storage, these compounds often undergo unwanted side reactions like glycation, deamidation, charge variation, and aggregation, which can compromise product safety and efficacy.</p><p>Finding robust and dependable ways to monitor these critical quality attributes (CQA) and protect therapeutic integrity is even more pressing, as regulatory agencies demand comprehensive characterizations.</p><p>While analytical techniques like liquid chromatography (LC) and mass spectrometry (MS) play a fundamental role in CQA analysis, the increasing complexity of analytical tasks is forcing the requirements of instruments to grow.</p><p>The good news?<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/blog/analyteguru/biopharma-boost-how-2d-lc-went-from-expert-only-to-routine/"><strong>Targeted two-dimensional LC (2D-LC)</strong></a> workflows that can handle analytical complexity and support straightforward method development without any manual fluidic changes are already here.</p><p>Let’s explore how your lab can use 2D-LC coupled with ultraviolet detection (UVD) or high-resolution accurate mass spectrometry (<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=22&amp;manufacturerItems=3"><strong>HRAM-MS</strong></a>) to monitor the CQAs of intact mAbs in real time (<strong>Figure 1</strong>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_2_8ee6b79638.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 1. Fluidic scheme of a 2D-LC-MS setup that supports multiple CQA analysis as well as method development without any manual replumbing." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_2_8ee6b79638.jpeg 224w," sizes="100vw" width="800" height="559"></p><div><h4><strong>Key takeaways</strong>:</h4><ul><li><strong>Why mAb variants matter</strong></li></ul><p>Physiochemical modifications generate diverse mAb variants — such as deamidated and aggregated species — that require monitoring to protect therapeutic efficacy and safety.</p><ul><li><strong>What switchable 2D-LC brings you</strong></li></ul><p>Switchable heart-cut 2D-LC workflows allow direct upstream monitoring of multiple CQAs during the production cycle from cell culture samples.</p><ul><li><strong>How the separation works</strong></li></ul><p>The mAb is purified from cell culture samples by protein A (ProA) affinity in the first dimension (<sup>1</sup>D). A high-performance strong cation exchange (SCX) column applied in the second dimension (<sup>2</sup>D) facilitates the separation of mAb charge variants or serves as a trap column to focus the purified mAb fraction prior to transfer to size exclusion chromatography (SEC).</p><ul><li><strong>Speed vs. depth: choosing the right detector</strong></li></ul><p>UVD monitoring provides quick and simple trendlines, while the direct coupling of <sup>2</sup>D with HRAM-MS allows deep characterizations and comprehensive insights into glycan profiles, modifications, and aggregates at the intact level.</p><ul><li><strong>Why at-line monitoring matters</strong></li></ul><p>Near real-time analysis of bioreactor samples enables earlier intervention, helping control material costs, improve yield, reduce off-target variants, and avoid costly downtime from rework or restarting production.</p></div><h3><strong>How 2D-LC workflows help streamline mAb manufacturing and prevent costly issues</strong></h3><p>Near real-time monitoring enables early intervention of issues, helping maintain product cost and quality, protect yield, and more consistent downstream performance.</p><p>As best practice, you should begin monitoring product quality attributes (PQAs) from the start of the cell culture and continue daily throughout the process until your reaction reaches the target yield (<strong>Figure 2</strong>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_3_bb3e594d4a.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 2. mAb titer calibration curve (left) and titer determination of cell culture samples from 1D ProA-UV (right). Samples were drawn from the bioreactors over 10 days." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_3_bb3e594d4a.jpeg 245w," sizes="100vw" width="768" height="282"></p><p>For established reactions, you can track changes in titer, charge, or size variant profiles based on UV spectral patterns quickly adjust feeds or cell harvest timing to prevent further issues during downstream processing.</p><p>Trends like the formation of new shoulders, slight peak shifts, or loss in peak intensity often signal changes in media composition, nutrient availability, pH, or process stress <strong>(Figure 3</strong>).</p><p><strong>For example:</strong></p><ul><li>Emerging acidic or basic species may indicate chemical modifications, like glycation, deamidation, or other stress‑related changes.</li><li>Size variants can reflect fragmentation or aggregation driven by temperature, agitation, or hold times.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_4_44dd018404.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 3. 2D chromatogram of ProA-SCX-SEC analysis of harvested cell culture samples drawn on days 2 and 9." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_4_44dd018404.jpeg 204w," sizes="100vw" width="768" height="587"></p><h3><strong>Why switchable workflows provide a simpler path to fewer surprises, faster course corrections, and more consistent mAb production</strong></h3><p>Fortunately,&nbsp;you&nbsp;don’t&nbsp;need a complicated,&nbsp;manual&nbsp;multistep&nbsp;analysis pipeline to keep your mAb production schedule on track. A streamlined, switchable 2D-LC-UV-MS workflow gives you fast, actionable insights—straight from the bioreactor<i>.</i>&nbsp;</p><p>The setup includes a<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/chromatography/liquid-chromatography-lc/hplc-uhplc-systems/vanquish-simple-switch-2d-lc.html"><strong>switchable fluidic design</strong></a> that lets you toggle between charge (SCX) and size variant analysis (SEC) without replumbing the hardware, providing complementary information.</p><p>This convenient approach <a target="_blank" rel="noopener noreferrer" href="https://www.youtube.com/watch?v=xOzYpxWbvQw"><strong>combines cleanup and analysis in one system</strong></a>, eliminating manual sample preparation and enabling direct analysis of cell culture supernatants from the bioreactor (<strong>Figure 4</strong>).</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_5_d6dc6b0059.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 4. Quality attribute monitoring of mAb biosynthesis by switchable 2D-LC-UV or MS workflow." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_5_d6dc6b0059.jpeg 245w," sizes="100vw" width="768" height="215"></p><h4><strong>How switchable 2D-LC technology works:</strong></h4><ul><li><strong><sup>1</sup>D.</strong> ProA affinity chromatography for titer determination and isolation of the mAb from host cell material and media components. The purified fraction is then sent via automated heart‑cut transfer straight into the <sup>2</sup>D. The <sup>1</sup>D elution conditions facilitate optimal mAb capture at the SCX column in the <sup>2</sup>D.</li><li><i><strong>ProA‑SCX to see charge drifts</strong>. </i>Gradient elution of the SCX column in the <sup>2</sup>D to separate acidic and basic variants from the main peak.</li><li><strong>ProA‑SCX‑SEC to see aggregation risks</strong>. The SCX column is switched in line with the SEC column to resolve the monomer, low‑molecular‑weight (LMW), and high‑molecular‑weight (HMW) fractions. The SCX column here acts as a trap and refocusing stage, releasing the mAb into SEC in a narrow band by a step increase to high ionic strength. The trap/elute procedure is critical to yield sharp peaks downstream, as SEC cannot refocus bands, broadened by the loop volume.</li></ul><p>Together, these workflows support both early risk detection and informed corrective action without adding analytical complexity.</p><h3><strong>UVD or MS? How to pick the right tool for the job</strong></h3><p>With switchable 2D-LC workflows, you can select different detection options in the <sup>2</sup>D: UVD or HRAM-MS (<strong>Figure 5</strong>). The fluidic setups differ slightly, but you must always use a fully volatile buffer system with the MS option.</p><h4><strong>Here’s how to choose the right setup:</strong></h4><ul><li><strong>UVD</strong> is ideal for routine, in‑time process control of established reactions. Provides <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_004276_hplc_vanquish_heartcut_2dlc_antibody_bioproduction_processes_an004276_na_en_201cb3360f.pdf"><strong>quick and simple</strong></a> trendlines when you need clear thresholds to act on, as well as straightforward decisions when you need day-to-day control of established processes. Like the “traffic light” for your production.</li><li><strong>HRAM-MS </strong>is best when you need detailed native intact‑level confirmation, glycoform profiling, or deeper characterization of modifications <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_003310_hplc_vanquish_2dlc_quality_attributes_mabs_an003310_na_en_8caddf8c25.pdf"><strong>during the development stage</strong></a> (<strong>Figure 5</strong>).</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_6_d039a60ac0.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 5. Coupling to UVD or HRAM MS in 2D charge variant analysis. Left: quick and straightforward batch comparison with the ProA-SCX-UV. Right: ProA-SCX-HRAM MS provides deep insights into glycoforms and modifications at the intact mass level." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_6_d039a60ac0.jpeg 245w," sizes="100vw" width="768" height="232"></p><h3><strong>Operational benefits your entire team can trust</strong></h3><p>Real-time monitoring of mAb CQAs reveals when you need to intervene and implement a bioprocess change, protecting you from the most expensive surprises: scrap costs, poor yield, off-target product, and the downtime it takes to clean and start over.</p><p>From an operations perspective, the benefits of switchable 2D-LC workflows are clear and practical (<strong>Figure 6</strong>).</p><ul><li>A single system performs at-line cleanup and analysis, reducing manual handling and process variability.</li><li>Heart-cut transfer minimizes sample loss and contamination risk, while the switchable design provides fit-for-purpose flexibility and delivers comprehensive insight into charge and size variants within one hour.</li><li>Regular daily sampling of crude cell culture supernatants directly from the bioreactor builds reliable trendlines over time.</li><li>Operators can quickly identify batch-divergent behavior using UVD to support timely process adjustments or perform deeper molecular characterization with HRAM MS.</li><li>A standardized, switchable workflow also supports method transfer across teams and sites, reducing variability during scale-up and method transfer.</li></ul><p>Fewer surprises, faster course corrections, and scaling operations without expert guidance are something analysts, engineers, quality control, finance, and regulatory bodies can all get behind.</p><h5><strong>Interested in using switchable 2D-LC workflows for your mAb manufacturing processes?</strong></h5><p>See real bioreactor data and step-by-step setup details in our application notes today.</p><ul><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_004276_hplc_vanquish_heartcut_2dlc_antibody_bioproduction_processes_an004276_na_en_201cb3360f.pdf"><strong>Switchable 2D-LC-UV workflows for routine monitoring</strong></a></li><li><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/an_003310_hplc_vanquish_2dlc_quality_attributes_mabs_an003310_na_en_8caddf8c25.pdf"><strong>Switchable 2D-LC-MS workflows for deeper characterizations</strong></a></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_7_d8882ed8ae.jpeg" alt="Thermo Fisher Scientific: Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS: Figure 6. Illustration showing how switchable 2D-LC works." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Fisher_Scientific_Monitoring_m_Ab_Manufacturing_the_Easy_Way_with_Switchable_2_D_LC_UV_MS_7_d8882ed8ae.jpeg 245w," sizes="100vw" width="768" height="384"></p><h3><strong>Frequently asked questions</strong></h3><div><div><h5><strong>1. What mAB quality control attributes should I monitor my reaction for regulatory?</strong></h5><p>Some of the most important critical quality attributes of cell culture derived samples you should monitor include mAb titer, charge and size variants, and glycosylation profiles.</p></div><div><h5><strong>2. What is 2D-LC?</strong></h5><p>2D-LC&nbsp;is a technique that successively uses two complementary LC modes for a multi-dimensional separation. Traditionally such systems are used for additional selectivity to help resolve complex separations or to deplete interfering matrices.</p></div><div><h5><strong>3. What is the benefit of using a switchable 2D-LC workflow for mAb manufacturing?</strong></h5><p>Switchable heart-cut 2D-LC workflows facilitate toggling&nbsp;between size and charge variant&nbsp;analysis of the intact mAb under native conditions — directly from cell culture samples — without reconfiguring&nbsp;the&nbsp;hardware.</p></div><div><h5><strong>4. Should I use UVD or MS during mAb manufacturing?</strong></h5><p>UVD supports quick, efficient decisions during production progression and is ideal for monitoring well-established biosynthetic processes. HRAM-MS allows for a deep characterization and comprehensive insights into glycan profiles, modifications, and aggregates at the intact level.</p></div></div><blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;</strong>#ChargeVariantAnalysis, #HRAM, #LiquidChromatography</p></blockquote>

Monitoring mAb Manufacturing the Easy Way with Switchable 2D‑LC-UV-MS

<p><span><strong>Time is running out to take advantage of discounted registration fees for the 19th Czech-Slovak Spectroscopic Conference (19th CSSC), one of the leading scientific events dedicated to spectroscopy and spectrometry in Central Europe. Researchers, students, instrument specialists, and industry professionals are invited to join the conference at the Faculty of Science, Palacký University Olomouc. The Early Bird registration period and the deadline for lecture and poster abstract submission both end on June 15, 2026.&nbsp;</strong></span></p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://cssc2026.spektroskopie.cz/registration_online"><strong>Online registration form</strong></a></p></blockquote><h4><strong>Registration Fees</strong></h4><h5><strong>Early (before June 15, 2026)</strong></h5><ul><li><strong>Participant (Member of IMMSS and SSS): </strong>10 000 CZK&nbsp;&nbsp;</li><li><strong>Participant (Non-member of IMMSS and SSS): </strong>14 000 CZK&nbsp;&nbsp;&nbsp;</li><li><strong>Students: </strong>7 000 CZK&nbsp;</li><li><strong>1-day registration:</strong> 5 000 CZK</li><li><strong>Accompanying person*: </strong>5 000 CZK</li></ul><h5><strong>Regular (after June 15, 2026)</strong></h5><ul><li><strong>Participant (Member of IMMSS and SSS): </strong>13 000 CZK&nbsp;&nbsp;</li><li><strong>Participant (Non-member of IMMSS and SSS): </strong>18 200 CZK&nbsp;&nbsp;&nbsp;</li><li><strong>Students: </strong>9 100 CZK&nbsp;</li><li><strong>1-day registration:</strong> 6 500 CZK</li><li><strong>Accompanying person*: </strong>6 500 CZK</li></ul><p><i>* The accompanying person does not have access to the scientific programme</i></p><p><strong>The conference fee is calculated with VAT</strong> and includes:</p><ul><li>attendance to lectures and poster session</li><li>book of abstracts (electronic version)</li><li>booklet</li><li>lunches, refreshments (coffee/tea breaks)</li><li>excursion</li><li>attendance at Welcome Party and Gala Dinner.&nbsp;</li></ul><p><strong>For an accompanying person</strong>, the conference fee includes the Welcome Party, the excursion and the Conference Dinner. The Conference Dinner is not included in the 1-day registration. This payment should be arranged with the Organising Committee.</p><p><i><strong>Accommodation is not included in the conference fee.</strong></i></p><h3><strong>Abstract submission</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://cssc2026.spektroskopie.cz/abstract_submission_online"><i><strong>ABSTRACT SUBMISSION FORM</strong></i></a></p><p><strong>Deadline</strong> for lecture/poster abstract submission <strong>is June 15, 2026</strong></p></blockquote><h4><strong>Posters</strong></h4><p>Prepare your poster in<strong> English in the format A0</strong> vertically orientated (portrait). The presence of one of the authors at the poster is requested during the poster session. Materials for mounting posters will be available on the poster panels.</p><h4><strong>Lectures</strong></h4><p>Prepare your <strong>presentation in English</strong> in <strong>PowerPoint</strong> of Portable Document Format (<strong>pdf</strong>), both in format <strong>16:9</strong> (widescreen). <strong>Invited and oral lectures</strong> takes <strong>30</strong> and<strong> 20 minutes </strong>(including discussion), respectively.&nbsp;</p><h3><strong>TOPICS &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;&nbsp;</strong></h3><h4><strong>Czech - Slovak Spectroscopic Conference</strong></h4><ul><li>Atomic spectrometry (AAS, ICP-MS, AFS, OES, speciation analysis, etc.)</li><li>Molecular spectrometry/spectroscopy (UV-Vis, NMR, IR, Raman, circular dichroism, etc.)</li><li>New techniques and data processing methods in IR and Raman spectroscopy, Special methods of Raman spectroscopy (resonance Raman, SERS, SERRS, TERS)</li><li>XRF spectrometry (EDS, WDS, XRF, PIXE, etc.)</li><li>Mass spectrometry &amp; hyphenated techniques</li><li>Instrumental radioanalytical methods (Gamma spectroscopy, NAA, etc.)</li><li>Laser spectroscopy and special spectroscopy techniques</li><li>Sample preparation and introduction techniques</li><li>Applications &nbsp;of atomic and molecular spectroscopy</li><li>Statistics and metrology in spectroscopy</li></ul><h4><strong>Mössbauer Spectroscopy in Material Science</strong></h4><ul><li>Environmental, catalytic, biologic, medical applications</li><li>Magnetism, magnetic nanoparticles, molecular magnets</li><li>Nanomaterials, nanostructures, nanocomposites, core-shell nanoparticles, thin films</li><li>Nanomaterials in biomedicine</li><li>Nuclear forward scattering in materials science</li><li>Solid-state chemistry and physics</li><li>Industrial applications, corrosion</li><li>Instrumentation, software</li><li>Earth Science, Mineralogy and Archaeology</li></ul><h4><strong>Venue</strong></h4><h5><strong>Faculty of Science</strong></h5><ul><li>Palacky University Olomouc</li><li>17. listopadu 1192/12, &nbsp;Olomouc, Czech Republic</li></ul>

19th CSSC 2026: Early Bird Registration and Abstract Submission Deadline Approaching

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Ioannes Marcus Marci Spectroscopic Society is a voluntary organization of scientific, scientific-pedagogical and professional workers in the field of spectroscopy, or legal entities engaged in scientific and application activities in this field, associated with joint activities. SSJMM was founded in 1949.

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<h3><strong>Pharma and biopharma fundamentals masterclasses</strong></h3><h5><strong>Build confidence in your analytical decisions across pharma and biopharma workflows</strong></h5><p>The pharma and biopharma fundamentals masterclasses are a year-long educational series designed for scientists who want to strengthen their knowledge, compare analytical strategies, and apply best practices across regulated workflows.</p><p>Each session focuses on a real analytical challenge — from quantitation and metabolite identification to biopharma characterization and extractables and leachables — with practical guidance from SCIEX experts.</p><p>Attend live or watch on demand and choose the sessions most relevant to your work.</p><h4><strong>Available now:</strong></h4><h5><strong>Pharma fundamentals: Metabolite Identification Metabolite identification is essential in drug discovery, supporting confident decisions in compound design and toxicology</strong></h5><p>This session shows how alternative fragmentation strategies can overcome limitations of traditional CID and improve MetID accuracy for complex metabolites.</p><ul><li><strong>Speaker: </strong>Heather Chassaing, Senior Accurate Mass Workflow Specialist, SCIEX</li></ul><h4><strong>Upcoming sessions</strong></h4><h5><strong>3. Pharma fundamentals: To Be or Not to Be? QQQ vs HRMS Quant</strong></h5><p>Discover how QQQ and HRMS stack up for quantitation in bioanalysis, from sensitivity to workflow efficiency. Learn best practices using SCIEX 7500+ and ZenoTOF 7600 systems to make confident, data-driven decisions.&nbsp;</p><blockquote><p><strong>Speaker:</strong> Cathy Lane, Sr. Application Lead, SCIEX</p><p>Cathy joined SCIEX in 2006 as a Support Specialist and in 2021 took up the role of EMEAI Applications Lead for Pharma &amp; Peptide Quant. She has 25 years’ experience in the development of LC-MS methods for the analysis of small and large molecules. She has a PhD in mass spectrometry-based proteomics from the University of London School of Pharmacy, an MSc in Forensic Science from King’s College London and an MA in Chemistry from the University of Oxford.</p></blockquote>

SCIEX: Pharma and biopharma fundamentals masterclasses

Pharma fundamentals: To Be or Not to Be? QQQ vs HRMS Quant

Pharma masterclass comparing QQQ vs HRMS quantitation with SCIEX 7500+ and ZenoTOF 7600 for confident bioanalysis decisions.

Biopharma fundamentals: LCMS Biopharma characterization

<div><p><strong>Persistent challenges in RNA manufacturing—such as immunogenic double-stranded RNA (dsRNA) impurities and unreliable quantitation methods—can limit product quality, scalability, and confidence in process decisions. These bottlenecks are increasingly critical as RNA is applied beyond vaccines into therapeutics and gene editing.</strong></p><p>This webinar explores practical strategies to reduce immunogenicity and improve RNA quality across manufacturing workflows. Attendees will gain insight into how purification and analytical approaches can enhance consistency and yield, alongside advances in quantitation methods that enable more reliable measurement.&nbsp;</p><p>Join to better understand how to optimize RNA purity and analysis to strengthen process control and downstream success.</p><h5><strong>Attend this webinar to:</strong></h5><ul><li>Identify and characterize dsRNA impurities in RNA manufacturing workflows</li><li>Apply purification strategies to reduce immunogenic byproducts and improve RNA quality across applications</li><li>Evaluate and validate analytical methods for accurate and reliable RNA quantitation</li><li>Use decision frameworks to integrate purification and measurement approaches for scalable, reproducible manufacturing</li></ul><blockquote><p><strong>Presenter:</strong> Nathaniel Clark, PhD ( Senior Scientist at Repligen Corporation)</p><p>Dr. Nathaniel Clark is a senior scientist at Repligen. He has a doctorate in biochemistry and structural biology from UMass Amherst and studied RNA as a postdoctoral researcher at the University of Texas. At Repligen, he uses structural biology, protein engineering, and modeling to design novel affinity resins.</p></blockquote></div>

Repligen: Improving RNA Purity and Measurement for Reliable Bioprocessing

Improving RNA Purity and Measurement for Reliable Bioprocessing

Optimize RNA purity and analysis. Learn to reduce immunogenic dsRNA impurities and validate analytical methods for reliable quantitation in RNA manufacturing

Improving RNA Purity and Measurement for Bioprocessing

<p><strong>Ion chromatography remains central to environmental water analysis, but the way established methods such as EPA 300 A/B and perchlorate are being applied today has evolved. Advances in eluent generation, column design, and system configuration are changing how laboratories approach sensitivity, robustness, and method reliability often without formally changing the method itself.</strong></p><p>This webinar focuses on recent, practical developments in the most widely used environmental IC applications. Topics include updated perchlorate workflows using potassium hydroxide eluents, modernized EPA 300 A/B approaches enabled by the most current column formats, and emerging strategies for haloacetic acid (HAA) analysis. The discussion goes beyond method names to examine how implementation options influence performance in routine laboratory use.</p><p>The session will be led by Metrohm IC experts Jay Gandhi and Linx Waclaski, who bring extensive hands‑on experience supporting environmental laboratories and developing practical IC workflows for regulated water analysis. Drawing from real‑world method optimization, troubleshooting, and application support, the speakers will connect today’s IC hardware and column advances to the challenges labs encounter every day. Attendees can expect technically grounded guidance that goes beyond theory, with insights shaped by direct experience helping environmental labs improve method performance, reliability, and efficiency.</p><h4><strong>Key Learning Objectives:</strong></h4><ul><li>Optimize IC methods for key environmental applications, including perchlorate, EPA 300 A/B, and haloacetic acids (HAAs)&nbsp;</li><li>Apply best practices to improve data quality, robustness, and reproducibility&nbsp;</li><li>Compare eluent and column strategies, including carbonate vs. hydroxide (KOH) workflows&nbsp;</li><li>Identify opportunities to increase sample throughout</li></ul><h4><strong>Who Should Attend:</strong></h4><ul><li>Environmental lab analysts performing water analysis by ion chromatography</li><li>Lab managers and supervisors seeking to improve data quality, robustness, and consistency</li><li>Laboratories looking to increase sample throughput and reduce analysis time</li><li>IC users interested in optimizing methods, including modern column strategies</li></ul><blockquote><p><strong>Speaker: </strong>Jay Gandhi, Ph.D. (Vertical Market Manager, Metrohm USA)</p><p><strong>Speaker:&nbsp;</strong>Linx Waclaski (Product Manager for Ion Chromatography, Metrohm USA)</p><p><strong>Speaker:</strong>&nbsp;Melissa O'Meara (Forensic Science Consultant, ACS Media Group)</p></blockquote>

Metrohm: New Approaches to Established Environmental IC Methods

New Approaches to Established Environmental IC Methods

Optimize environmental water analysis by ion chromatography. Learn advanced column strategies and workflows for perchlorate, EPA 300 A/B, and HAAs.

<p><strong>In this webinar, Fred Foster, Applications Scientist at GERSTEL, Inc., will introduce GERSTEL’s automated sample preparation systems, then transition to a multi-omics presentation by Noah Smeriglio, Ph.D. Candidate in Chemistry, and Gwangbin Lee, Ph.D. in Chemistry, Postdoctoral Associate at the University of Maryland.</strong></p><p>This presentation will highlight an automated, integrated multi-omics workflow for extracting proteins, lipids, and metabolites from a single sample using the GERSTEL MPS platform. Validated across cell and tissue samples and coupled with LC-MS/MS analysis, the workflow enables reproducible, high-throughput multi-omics studies in complex biological applications.</p><h5><strong>You will learn how to:</strong></h5><ul><li>Optimize key parameters in your workflow</li><li>Improve recovery and reproducibility of proteins, lipids, and metabolites</li><li>Increase throughput for complex biological samples</li></ul><h5><strong>Full Abstract</strong></h5><p>Mass-spectrometry-based omics technologies have enabled the comprehensive characterization of diverse types of molecules, such as proteins, lipids, and metabolites, across biological systems. Integration of multiple molecular classes from the same sample reduces variability and enables system-level insights into biology and disease. However, conventional sample preparation methods using Folch or MTBE extraction are labor-intensive, susceptible to variability, and difficult to scale for high-throughput applications. Here, we developed an automated and integrated multi-omics sample preparation workflow using the GERSTEL MPS platform. Key experimental parameters were systematically optimized to achieve robust and reproducible recovery of proteins, lipids, and metabolites from a single sample. The workflow was validated across both cell and tissue samples, demonstrating strong reproducibility and scalability. Coupled with LC-MS/MS analysis, this platform was used to analyze over 60 brain samples from a neurodevelopmental disorder mouse model, achieving the identification and quantification of over 10,000 proteins, 2,000 lipids, and 700 metabolites. In summary, this automated multi-omics workflow provides a robust and scalable solution for high-throughput MS-based multi-omics studies.</p><blockquote><p><strong>Presenter: </strong>Fred Foster (Applications Scientist, GERSTEL, Inc.)</p><p><strong>Presenter: </strong>Noah Smeriglio, Ph.D. (Candidate, Chemistry, University of Maryland)</p><p><strong>Presenter: </strong>Gwangbin Lee (Postdoctoral Associate, Ph.D. in Chemistry, University of Maryland)</p></blockquote>

GERSTEL: An Automated Sample Preparation Platform for Integrated Proteomics, Lipidomics, and Metabolomics

An Automated Sample Preparation Platform for Integrated Proteomics, Lipidomics, and Metabolomics

Automate multi-omics sample prep. Learn to extract proteins, lipids, and metabolites from a single cell or tissue sample using the GERSTEL MPS platform

Automated Sample Prep for Multi-Omics Workflows

<h3><strong>Bringing laboratory automation to life with Andrew+ and OneLab</strong></h3><p>This webinar series explores how Andrew+ automated liquid handling and OneLab workflow software support consistent, traceable and efficient laboratory operations. Through application‑focused episodes, you will see how automation can be successfully integrated into everyday laboratory workflows, from method development to routine and regulated environments, supported by real‑world customer experiences and testimonials.</p><h4><strong>Episode 4 – Food &amp; Environmental Workflows</strong></h4><h4><span style="color:#212121;"><strong>Overview</strong></span></h4><p>Food and environmental testing laboratories face complex matrices, high sample volumes and strict quality requirements. This episode highlights how automation helps standardise sample preparation while reducing manual workload and operational risk, with <strong>direct insight from laboratories applying these solutions in routine testing.</strong></p><h4><span style="color:#212121;"><strong>Key highlights</strong></span></h4><ul><li>Standardise sample preparation in complex food and environmental matrices</li><li>Improve repeatability by automating pipetting and solid phase extraction (SPE) workflows</li><li>Support auditing, troubleshooting and regulatory needs through automated workflow documentation</li></ul><blockquote><p><strong>Speaker: Xavier Rodriguez </strong>(Principal Applications Specialist, Chemistry, Europe - Waters Corporation)</p><p>Xavier is part of the European Market Development Team. He works as an Application Specialist with focus on sample prep and has more than 20 years of experience in solving sample prep challenges.</p><p><strong>Customer testimonials: Labexia </strong>– Groupe CARSO</p><p>Labexia is part of Groupe CARSO, a European analytical services group specialising in food testing, environmental analysis and routine laboratory services.</p><p>In this episode, Labexia shares how automation has been implemented in day‑to‑day food testing workflows to streamline pipetting and sample preparation activities. The testimonial illustrates how automated liquid handling helps free up technicians’ time, improve repeatability and reduce the risk of musculoskeletal strain in routine laboratory operations.</p></blockquote><h5><strong>Reserve Your Spot Today!</strong></h5>

Transform Your Daily Lab Operations with Automation - Food and Enviromental Workflows

Automate food and environmental testing workflows. Learn how Andrew+ and OneLab standardize sample prep, automate SPE, and improve laboratory traceability

Automated Food & Environmental Lab Workflows

<div><h4><strong>Overview</strong></h4><p>Most of what happens inside a tissue, a tumor, or a 3D cell model is chemically invisible to conventional analysis. The molecular organization is there. The spatial relationships are there. MALDI Imaging is now the tool that makes them visible, from individual cells to complex tissue architectures. This webinar explores what that visibility looks like at the frontier.</p><p>In this webinar, <strong>Prof. Hopf (CeMOS, TH Mannheim)</strong> will present his group's latest findings across the full range of MALDI Imaging-based spatial analysis, from established tissue workflows to single-cell imaging and complex biological systems.</p><p>Starting with well‑established tissue workflows, the talk will demonstrate how spatial molecular analysis can uncover altered metabolic and proteomic phenotypes linked to differentiation, disease, or chemical exposure. A particular focus will be placed on toxicology‑relevant applications, showing how label‑free MALDI Imaging enables the unambiguous molecular identification of protein accumulations in kidney tissue, supporting reliable decision‑making in preclinical safety assessment where conventional histology and immunohistochemistry reach their limits.</p><p>The webinar will then focus on two rapidly developing fields: single‑cell molecular imaging for dissecting cellular activation states, and 3D biology. 3D data. 3D visualization. All in one workflow. Hopf's group applies MALDI Imaging to 3D cell culture disease models including organoids and spheroids, generating volumetric spatial molecular data that can be explored end-to-end in mixed reality, from sample to insight, the geometry is preserved throughout.</p><p>Finally, advanced data reconstruction and visualization strategies will be presented that enable researchers not only to analyze but to interactively explore spatial molecular landscapes in mixed reality, opening new perspectives for spatial biology, toxicological research, and translational and pharmaceutical applications.</p><h4><strong>Key Learning Objectives</strong></h4><ul><li>See how MALDI Imaging extends spatial molecular analysis beyond conventional tissue sections into single cells and complex biological systems</li><li>Learn how molecular imaging supports toxicological decision‑making through label‑free, in situ protein identification</li><li>Experience how mixed reality visualization transforms the way researchers interact with complex spatial molecular datasets</li><li>Gain insight into advanced workflows and visualization strategies for complex spatial datasets</li><li>Discover how MALDI Imaging contributes to biological, pharmaceutical, and safety‑related research</li></ul><h4><strong>Who Should Attend</strong></h4><ul><li>Researchers in spatial biology and imaging mass spectrometry</li><li>Scientists working in metabolomics, lipidomics, proteomics, and tissue analysis</li><li>Toxicologists and pharmaceutical researchers involved in preclinical safety assessment</li><li>Researchers interested in single-cell and 3D spatial omics approaches</li><li>Drug discovery scientists using 3D tissue models or organoids for target identification or compound profiling</li><li>Analytical and translational scientists working on biologics, ADCs, or LNP spatial distribution characterization</li></ul><blockquote><p><strong>Presenter:</strong> Carsten Hopf, Ph.D. (Professor and Head, Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Technische Hochschule Mannheim, Germany)</p><p>Prof. Hopf's group at CeMOS has contributed foundational methods in MALDI-based spatial proteomics, metabolomics, and tissue model imaging, with applications ranging from neuroscience to toxicological safety assessment. His group's 3D MALDI Imaging platform was recently published in Advanced Science (2026).<br>&nbsp;</p></blockquote></div>

Bruker: MALDI Imaging at the Frontier - Single-Cell Analysis

MALDI Imaging at the Frontier: Spatial Metabolomics, Single-Cell Analysis, and 3D Exploration in Mixed Reality

Advance drug discovery with MALDI Imaging. Explore how spatial metabolomics, single-cell analysis, and 3D mixed reality accelerate preclinical research.

MALDI Imaging Frontier: 3D Spatial Biology Trends

<h4><strong>Key Learning Points</strong></h4><ul><li>Understand the correct steps to take when first receiving a new column, including inspection procedures and initial test runs.</li><li>Learn practical techniques to extend column lifetime and maintain performance over time.</li><li>Identify when a column should be retired by recognizing key end-of-life indicators.</li><li>Apply best practices for column conditioning, activation, and proper storage.</li></ul><h4><strong>Who Should Attend</strong></h4><p>Any analysts and scientists routinely working with HPLC/UHPLC columns who want practical care, maintenance, and lifetime‑extension tips.&nbsp;</p><blockquote><p><strong>Presenter: </strong>Duilio Romanello (Senior Technical Specialist, Phenomenex)</p><p>Duilio Romanello earned his MSc in Pharmaceutical Chemistry and Technology from the University of Bologna. He joined Phenomenex in 2008 as an Inside Technical Sales Consultant, later leading GC/SPE and Env/Food teams in Italy. Since 2016, he has been Account Manager for Southern Italy and GC Specialist. In 2023, he became Senior Technical Specialist for Phenomenex’s Technical team supporting scientists globally with method development, troubleshooting, and application support.</p></blockquote>

Phenomenex: Tips for Getting the Best Out of Your LC Phenomenex Column

Tips for Getting the Best Out of Your LC Phenomenex Column

Discover best practices for HPLC/UHPLC column care, conditioning, storage, troubleshooting, and lifetime extension.

Getting Best Out of Your LC Phenomenex Column

<p><strong>Migrating legacy LC Method doesn't have to introduce risk</strong></p><p>In regulated QC environments, LC method migration requires confidence, consistency, and control. This webinar explores how a structured, automated approach can help QC laboratories transition legacy LC methods to Alliance™ iS while maintaining compliance, method integrity, and operational continuity.</p><h5><strong>What you will learn</strong></h5><ul><li>How an automated Empower™ workflow enables confident, compliant migration of legacy LC methods to Alliance™ iS in regulated QC environments</li><li>Best practices for transitioning legacy LC methods while preserving method intent, system suitability, and data integrity</li><li>How a risk‑based migration strategy can support long‑term QC efficiency, performance, and laboratory scalability</li></ul><h5><strong>Who should attend</strong></h5><ul><li>Analyst, Supervisors and Lab Managers working in QC Pharmaceuticals Quality Control Labs<br>&nbsp;</li></ul><blockquote><p><strong>Presenter: </strong>Andrea Gheduzzi (Principal LC Market Dev. Manager, EMEA, Waters Corporation)</p><p>Andrea Gheduzzi, is a principal LC market development manager for EMEA at Waters Corporation. Andrea Gheduzzi has spent more than 30 years in the chromatography field. Across his career he had various roles, service engineer, chromatography lab manager position, and technical manager for chromatography columns.</p><p>He has mainly been dealing with pharma accounts, also supporting LC method development activities using DoE/QbD approaches. In his previous role as Pharma Business Development Manager at Waters he has further expanded his expertise in AQbD and related applications.</p><p>Since 2023 he became principal LC market development manager for EMEA and member of the AQbD working party at the EDQM.</p></blockquote>

Waters Corporation: De‑Risking LC Method Migration: Transitioning Legacy Methods to Alliance™ iS System in Regulated QC Labs

De‑Risking LC Method Migration: Transitioning Legacy Methods to Alliance™ iS System in Regulated QC Labs

Smooth LC method migration to Alliance iS. Discover automated Empower workflows to maintain compliance and data integrity in regulated pharma QC labs

De‑Risking LC Method Migration

<p><strong>We are pleased to invite you to our upcoming free online webinar focused on one of the most pressing challenges in environmental monitoring and water quality management — PFAS (Per- and Polyfluoroalkyl Substances).</strong></p><p>As regulatory frameworks continue to evolve and compliance deadlines approach, laboratories, water utilities, and environmental professionals need robust, reliable, and cutting-edge analytical solutions to stay ahead.</p><h4><strong>🎤 Our Speaker</strong></h4><p>The webinar will be hosted by <strong>Jana Kováčová, Ph.D., PFAS Regional Lead for Continental Europe Environmental Division</strong>, who has dedicated the last several years to the field of PFAS analysis and determination in ALS laboratories. Jana is a recognized expert in PFAS environmental analytics and will share practical insights and the latest developments in analytical strategies to help your organization achieve and maintain compliance.</p><h4><strong>🎯 What You Will Learn</strong></h4><ul><li>Latest <strong>regulatory developments</strong> and compliance requirements for PFAS in water, including <strong>EU Drinking Water Directive 2020/2184</strong> and its implications for water suppliers and laboratories.</li><li><strong>Regulatory updates for surface water and groundwater</strong> — what's new and what to expect next.</li><li>Overview of <strong>advanced analytical strategies</strong> for PFAS detection and quantification in water matrices and how we analyse PFAS samples.</li><li>Key <strong>analytical challenges</strong> associated with PFAS testing — from ultra-trace detection to matrix interferences and contamination control.</li><li>The critical importance of using tested <strong>sampling containers</strong> and sample preservation to ensure reliable results.</li><li>Illustrative <strong>examples of results</strong> from real-world PFAS water analyses.</li><li>How ALS can support your needs with <strong>accredited PFAS testing services</strong>.</li></ul><h4><strong>👥 Who Should Attend</strong></h4><p>This webinar is designed for our clients, professionals, laboratory and technical staff, scientists, as well as anyone with an interest in analytical chemistry who wants to better understand the occurrence of these "forever chemicals" in the environment. &nbsp;</p><h4><strong>💬 Q&amp;A Session</strong></h4><p>There will be a live Q&amp;A session at the end of the webinar. You are welcome to submit your questions in advance during registration or ask them live on the day.</p><h4><strong>📅 Additional Webinar Info:</strong></h4><ul><li><strong>Platform: </strong>Microsoft Teams (online)</li><li><strong>Language: </strong>English</li><li><strong>Duration:</strong> approx. 45 - 60 minutes (incl. Q&amp;A)<br>Extras: If you are unable to attend on the day, please register and we will provide you with the recording of the webinar.</li></ul><h4><strong>🔬 About ALS Environmental</strong></h4><p>ALS is a global leader in environmental testing and analytical services, providing accredited PFAS analysis to clients across Europe and beyond. Our dedicated PFAS experts help clients navigate the complex regulatory landscape with confidence.</p><p>For further information, please contact us on: <strong>marketing.cz@alsglobal.com</strong></p><p>We look forward to welcoming you to this important discussion on PFAS compliance in water.</p><blockquote><p><strong>Speaker</strong> Jana Kováčová (PFAS Regional Lead - Continental Europe)</p><p>Jana Kováčová is an analytical chemist with over 15 years of experience in method development and validation. She earned her MSc and PhD from the University of Chemistry and Technology, Prague (UCT Prague), where she specialized in analytical methods for pesticide residue determination in water and food matrices of both plant and animal origin. In 2020, Jana joined ALS Czech Republic as a Validation Specialist within the environmental analytical innovations group, later transitioning to a full-time focus on PFAS (per- and polyfluoroalkyl substances) analytics. In 2022, she was appointed Supervisor of the PFAS Section. Currently, Jana serves as the PFAS Lead for Continental Europe. In this role, she coordinates ALS’s PFAS analytical activities across the region, acting as a key technical representative for PFAS topics. She supports laboratories and clients with strategic guidance and data interpretation, aligns testing approaches across multiple sites, and ensures consistent, high-quality delivery. To stay at the forefront of the field, Jana closely monitors legislative updates and emerging trends, sharing her expertise through client webinars, seminars, and presentations at scientific conferences.</p></blockquote>

ALS: PFAS in Water 2026: Achieving Compliance through Advanced Analytical Strategies

PFAS in Water 2026: Achieving Compliance through Advanced Analytical Strategies

Join ALS experts to explore PFAS regulations, water testing challenges, analytical methods, and compliance strategies for environmental monitoring.

PFAS in Water - Analytical strategies

<div><div container-id="cq-colctrl-lt0" comp-id="A1"><div><p><strong>Join us for a free, hands-on Thermo Scientific™ Proteome Discoverer™ software online workshop. This session is designed to walk you through the latest best practices for Data Independent Acquisition (DIA) analysis, featuring the powerful new DIA-NN node.</strong></p><p>Whether you are a novice or an intermediate user, this workshop provides the practical knowledge needed to leverage the novel InfinDIA mode for ultra-fast analysis against unlimited search spaces</p><h4><strong>What We’ll Cover</strong></h4><ul><li><strong>Proteome Discoverer 3.3 SP1 updates: </strong>A deep dive into the latest release, including news, installation, and licensing.</li><li><strong>DIA-NN &amp; InfinDIA:</strong> Guest speaker Vadim Demichev introduces DIA-NN 2.5 and the breakthrough InfinDIA mode for handling near-unlimited search spaces and selected applications.</li><li><strong>Practical processing walkthrough: </strong>Michaela Scigelova leads a step-by-step guide using DIA-NN:<ul><li>training materials, study, analysis</li><li>workflow parameter settings</li><li>DIA-NN node (discussion of all parameters, recommendet settings)</li><li>Results review</li></ul></li><li><strong>Tips for efficient data processing</strong></li></ul><p><i>Can’t attend the live broadcast? Register anyway! All registrants will receive a link to the session recording.</i></p><blockquote><p><strong>Presenter: </strong>Michaela Scigelova (Product Support, Thermo Fisher Scientific)</p><p>Michaela provides customer support to Thermo Scientific Proteome Discoverer software users.</p><p><strong>Presenter: </strong>Vadim Demichev (MSTARS Group Leader, Charité - Universitätsmedizin Berlin)</p><p>Vadim Demichev is a founder of Aptila Biotech and a research group leader at the Charité – Universitätsmedizin Berlin, focusing on developing of LC-MS methods and data analysis approaches for quantitative proteomics.</p></blockquote></div></div></div>

Thermo Fisher Scientific: Proteome Discoverer 3.3 SP1: Processing DIA data with DIA-NN node

Proteome Discoverer 3.3 SP1: Processing DIA data with DIA-NN node

Join this workshop to explore DIA-NN, InfinDIA, and Proteome Discoverer 3.3 SP1 for efficient DIA proteomics data analysis and review.

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