2D-LC/MS in a regulated biopharma environment: Challenges & applications (Arnaud Delobel, MDCW 2023)

Mo, 13.11.2023
| Original article from: The Multidimensional Chromatography (MDC) Workshop
2D-LC/MS in a regulated biopharma environment: Challenges & applications
Video placeholder
  • Photo: 2D-LC/MS in a regulated biopharma environment: Challenges & applications (Arnaud Delobel, MDCW 2023)
  • Video: LabRulez: Arnaud Delobel: 2D-LC/MS in a regulated biopharma environment: Challenges & applications (MDCW 2023)
  • 🎤 Presenter: Arnaud Delobel (R & D and Innovation Director, Quality Assistance SA)

💡 Book in your calendar: 15th Multidimensional Chromatography Workshop (MDCW) January 2024

15th Multidimensional Chromatography (MDC) Workshop 2024

Table of Content

  • Quality Assistance sa
  • 2D-LC/MS at Quality Assistance
  • Multiple Heartcut 2D-LC in practice
  • Characterisation of ADCs by HIC-RP/MS
  • Advanced use of 2D-LC/MS with at-column-dilution technology
  • What’s next?
  • Take-home messages
The Multidimensional Chromatography (MDC) Workshop
 

Related content

Seznámení s přístroji Wyatt Technology

Instrumentation
GPC/SEC
Manufacturer
Waters
Industries
---

Your Essential Guide to Sugar Analysis with Liquid Chromatography

Instrumentation
Sample Preparation, Consumables, Software, HPLC, LC/MS, LC/SQ
Manufacturer
Waters
Industries
Food & Agriculture

GPC/SEC Troubleshooting and Good Practice

Instrumentation
GPC/SEC
Manufacturer
Agilent Technologies
Industries
---

Speciation of Iron in Lithium Iron Phosphate (LFP) Cathode Material by LC-ICP-MS

Instrumentation
HPLC, ICP/MS, Speciation analysis
Manufacturer
Agilent Technologies
Industries
Energy & Chemicals , Materials Testing

LC/MS/MS Method Package for Sugars and Sugar Nucleotides

Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Shimadzu
Industries
Pharma & Biopharma
 

Related articles


Presentation | Video

Unsupervised optimization of heart-cut and comprehensive 2D-LC separations (Bob Pirok, MDCW 2023)

This presentation will discuss the current challenges to scale this automated method development technology to heart-cut and comprehensive 2D-LC separations.

Presentation | Video

2D-LC with solvent modulation to overcome the mobile phase incompatibility (Marie Pardon, MDCW 2023)

This study investigates possible configurations for the modulation of HILIC and RPLC using ASM in a selective comprehensive 2D-LC set-up (sHILIC x RPLC).

Presentation | Video

Temperature-responsive & chiral chromatography for chiral pharmaceuticals (Turaj Rahmani, MDCW 2023)

In this study, the enantioselective separation of a wide range of medicinal substances (log p: 0.9-4.1) is evaluated using a combination of TRLC and Chiral-RPLC.
 

Related articles


Presentation | Video

Unsupervised optimization of heart-cut and comprehensive 2D-LC separations (Bob Pirok, MDCW 2023)

This presentation will discuss the current challenges to scale this automated method development technology to heart-cut and comprehensive 2D-LC separations.

Presentation | Video

2D-LC with solvent modulation to overcome the mobile phase incompatibility (Marie Pardon, MDCW 2023)

This study investigates possible configurations for the modulation of HILIC and RPLC using ASM in a selective comprehensive 2D-LC set-up (sHILIC x RPLC).

Presentation | Video

Temperature-responsive & chiral chromatography for chiral pharmaceuticals (Turaj Rahmani, MDCW 2023)

In this study, the enantioselective separation of a wide range of medicinal substances (log p: 0.9-4.1) is evaluated using a combination of TRLC and Chiral-RPLC.
 

Related articles


Presentation | Video

Unsupervised optimization of heart-cut and comprehensive 2D-LC separations (Bob Pirok, MDCW 2023)

This presentation will discuss the current challenges to scale this automated method development technology to heart-cut and comprehensive 2D-LC separations.

Presentation | Video

2D-LC with solvent modulation to overcome the mobile phase incompatibility (Marie Pardon, MDCW 2023)

This study investigates possible configurations for the modulation of HILIC and RPLC using ASM in a selective comprehensive 2D-LC set-up (sHILIC x RPLC).

Presentation | Video

Temperature-responsive & chiral chromatography for chiral pharmaceuticals (Turaj Rahmani, MDCW 2023)

In this study, the enantioselective separation of a wide range of medicinal substances (log p: 0.9-4.1) is evaluated using a combination of TRLC and Chiral-RPLC.
 

Related articles


Presentation | Video

Unsupervised optimization of heart-cut and comprehensive 2D-LC separations (Bob Pirok, MDCW 2023)

This presentation will discuss the current challenges to scale this automated method development technology to heart-cut and comprehensive 2D-LC separations.

Presentation | Video

2D-LC with solvent modulation to overcome the mobile phase incompatibility (Marie Pardon, MDCW 2023)

This study investigates possible configurations for the modulation of HILIC and RPLC using ASM in a selective comprehensive 2D-LC set-up (sHILIC x RPLC).

Presentation | Video

Temperature-responsive & chiral chromatography for chiral pharmaceuticals (Turaj Rahmani, MDCW 2023)

In this study, the enantioselective separation of a wide range of medicinal substances (log p: 0.9-4.1) is evaluated using a combination of TRLC and Chiral-RPLC.