Agilent 6430 Series LC/QQQ (Refurbished)

The Agilent 6430 Series LC/MS Triple Quadrupole (LC/QQQ) Mass Spectrometer is designed for quantitative analysis and targeted mass spectrometry applications. Part of Agilent’s portfolio of liquid chromatography-triple quadrupole mass spectrometers, it offers high sensitivity, precision, and robustness, making it suitable for various applications in pharmaceuticals, environmental analysis, food safety, and clinical research.

Key Features:

• Dynamic MRM: Allows up to 4,000 transitions for comprehensive, targeted analyses.
• Fast Polarity Switching: Switches polarity in just 30 ms for efficient multi-ion monitoring.
• Low Dwell Times: 1 ms dwell times ensure fast data acquisition without cross-talk.
• High Sensitivity: Achieves low attomole sensitivity, especially effective for peptide quantitation.
• MassHunter Software: Streamlines control with reliable automation and optimization.
• HPLC-Chip/MS Compatibility: Integrates with microfluidic technology for robust, high-sensitivity nanospray applications.

Technical Specifications:

Mass Spectrometer Specifications

• Mass Analyzer: Triple quadrupole with Q1 and Q3 quadrupoles for mass filtering and Q2 collision cell.
• Mass Range:
  • Q1 and Q3 Mass Range: 2–1,250 m/z.
• Resolution: Adjustable resolution; unit mass resolution at 0.7 FWHM.
• Polarity Switching:
  • Switching Time: 30 ms.
• Enables rapid transition between positive and negative ionization modes, essential for multi-ion assays.

Sensitivity and Detection

    Sensitivity: Achieves low attomole sensitivity, especially in peptide quantitation applications with HPLC-Chip integration.

• MRM (Multiple Reaction Monitoring):
  • Dynamic MRM Capabilities: Supports up to 4,000 transitions.
• Dwell Time: Down to 1 ms with no cross-talk, allowing high-speed data acquisition.
• LOQ (Limit of Quantitation): Dependable low attomole sensitivity in peptide analysis.
• Noise Reduction: Dual turbo pump in the Q3 region to enhance ion transmission and reduce chemical noise.

Software Control and Automation

• Control Software: MassHunter Workstation.
• Features: Automates compound optimization via MassHunter Optimizer and Peptide Optimizer.
• Dynamic MRM Method Creation: Allows transition lists to be built dynamically during LC separations based on retention time windows.
• Regulatory Compliance: Supports 21 CFR Part 11 compliance for validated workflows in regulated environments.
• Peak Integration: Requires at least 10 data points per peak for reliable quantitation, making it suitable for UHPLC’s narrow peaks.

Laboratory requirements

• Operating Temperature Range: 15°C to 35°C (recommended stable lab environment).
• Dimensions:
  • Width: 110 cm
  • Depth: 70 cm
  • Height: 80 cm
• Weight: Approx. 150 kg.
• Power Requirements: 230V AC, 50/60 Hz; specific configurations vary based on additional modules and accessories.

Key Advantages:

• Efficiency in Complex Analyses: Dynamic MRM methods optimize cycle times, allowing precise quantitation of hundreds of compounds in a single run.
• Exceptional Sensitivity and Reliability: With low attomole detection limits and robust nanospray capabilities, the 6430 system is ideal for advanced biomarker validation.
• Seamless Integration: Integrates with Agilent 1290 Infinity LC and HPLC-Chip/MS for high-throughput, low-maintenance workflows.
• Cost-Effective Operation: Provides high reliability with minimal cross-talk and reduced chemical noise, leading to lower operational costs.

Why Choose Refurbished?

Purchasing a refurbished items from LabRulez provides exceptional value without compromising on quality. Our refurbishment process includes:

• Thorough Inspection and Testing: Each unit undergoes rigorous testing to ensure it meets original performance specifications.
• Updated Components: All critically worn or malfunctioning components and materials are replaced with new ones to extend the life and reliability of the modules after installation and to meet all manufacturer's performance requirements.
• Cost Efficiency: Save up to 70% of the cost compared to buying a new module or part, freeing up budget for other important lab expenses.

Why Buy from LabRulez?

LabRulez is committed to providing high-quality, reliable laboratory equipment at competitive prices. With our extensive experience in refurbishing and reselling scientific instruments, we guarantee:

• Expert Support: Our fully trained and experienced team of specialists is available to assist with installation, operation, and troubleshooting.
• Flexible Payment Options: Choose from a range of payment methods that suit your procurement process.
• Fast and Secure Shipping: Get your equipment delivered quickly and safely to your lab.