Agilent 1260 Infinity HPLC Evaporative Light Scattering Detector (G4218A) (Refurbished)

The Agilent 1260 Infinity Evaporative Light Scattering Detector (ELSD) G4218A is a highly versatile analytical instrument designed for use in high-performance liquid chromatography (HPLC), micro-HPLC, gel permeation chromatography (GPC), and counter-current chromatography (CCC). This detector employs a universal detection method, capable of identifying non-volatile analytes without dependence on their UV absorption properties. As a result, it is highly effective for compounds that lack chromophores, offering greater flexibility in solvent choice, including UV-absorbing solvents.

The detection process is based on three core principles: nebulization, solvent evaporation, and detection of analyte particles. By converting the eluent into fine mist, evaporating the solvent, and measuring the scattered light using a photomultiplier tube, the ELSD ensures precise and reliable results. Compact, efficient, and intuitive, the G4218A integrates seamlessly into laboratory workflows, providing accurate data essential for critical research and applications.

Technical Specifications

General Specifications:

• Detection Method: Evaporative light scattering
• Light Source: High-efficiency blue LED
• Detector: High-sensitivity photomultiplier
• Temperature Range: Ambient to 100°C

Flow Rate and Gas Requirements:

• Eluent Flow Rates:
  • Micro Flow Nebulizer: 5 µL/min to 50 µL/min
  • Semi-Micro Flow Nebulizer: 40 µL/min to 1 mL/min
  • Standard Flow Nebulizer: 500 µL/min to 2 mL/min
  • Large Flow Nebulizer: 1.5 mL/min to 5 mL/min
  • Rapid Resolution Nebulizer: 0.2 mL/min to 1.4 mL/min
• Gas Flow Control: Manual or computer-controlled
• Gas Pressure: 3.5 bar (51 psi) typical; range 3 bar (44 psi) to 4.5 bar (67 psi)
• Gas Consumption: < 4 L/min (Large Flow Nebulizer); < 3 L/min (other nebulizers)

Electrical and Interface Specifications:

• Power Supply: 100 V / 2.1 A, 115 V / 60 Hz, 1.8 A, or 230 V / 50 Hz, 1.7 A
• Interface Options: RS-232 for data output and system control
• Signal Output: 0–1000 mV (analog), RS-232 (digital)

Physical Dimensions and Weight:

• Dimensions: 250 mm (W) x 450 mm (H) x 550 mm (D)
• Weight: 18.5 kg (40 lbs)

Operating Parameters:

• Signal Drift: < 1 mV/h
• Signal Noise: < ±1 mV

This detector offers robust design and advanced control features, including both manual and automated operation modes, ensuring compatibility with modern laboratory systems​.