Agilent 1290 Infinity series HPLC Autosampler G4226A (Bazaar)

The Agilent 1290 Infinity Series Autosampler G4226A is an integral component of the Agilent 1290 Infinity Liquid Chromatography (LC) System, designed to enhance analytical performance through precise sample handling and injection capabilities. It is engineered to meet the rigorous demands of modern high-performance liquid chromatography (HPLC), offering enhanced robustness, speed, and flexibility. Featuring advanced technology, the G4226A provides high throughput, minimized carryover, and seamless compatibility with various sample containers such as vials and well plates. With its broad pressure range of up to 1200 bar and compatibility with sub-two-micron column technology, the autosampler is ideal for high-resolution and high-sensitivity analyses. Its design emphasizes operational efficiency, from overlapped injections to optimized leak and waste management.

Technical Specification

Physical Specifications

• Weight: 15.5 kg (34.2 lbs)
• Dimensions (H × W × D): 200 mm × 345 mm × 440 mm (8 in × 13.5 in × 17 in)
• Power Requirements:
  • Line Voltage: 100 – 240 V~, ± 10%
  • Line Frequency: 50 or 60 Hz, ± 5%
  • Power Consumption: 200 VA / 200 W / 683 BTU
• Operating Temperature Range: 4–55 °C (39–131 °F)
• Storage Temperature Range: -40–70 °C (-40–158 °F)
• Operating Altitude: Up to 2000 m (6562 ft)
• Non-operating Altitude: Up to 4600 m (15092 ft)
• Humidity: < 95% relative humidity at 40 °C (non-condensing)

Performance Specifications

• Injection Volume Range:
  • Standard: 0.1 – 20 µL in 0.1 µL increments
  • Expanded: Up to 40 µL with a 40 µL loop, and up to 120 µL with a large-volume injection kit (pressure range up to 1200 bar)
• Precision:
  • <0.25% RSD for 5–20 µL
  • <0.5% RSD for 2–5 µL
  • <0.7% RSD for 1–2 µL
• Pressure Range: Up to 1200 bar (600 bar with certain upgrades)
• Sample Viscosity Range: 0.2 – 5 cp
• Sample Capacity:
  • 2 × well plates (MTP) + 10 × 2 mL vials
  • 108 × 2 mL vials in 2 × 54 vial plates + 10 additional 2 mL vials
  • 30 × 6 mL vials in 2 × 15 vial plates
  • Compatible with the Agilent 1200 Series sample capacity extension
• Injection Cycle Time: Typically <21 s for a 5 µL injection volume
• Carryover: Typically <0.004%

Control and Communication

• Software Compatibility:
  • Agilent ChemStation for LC (B.04.02 or above)
  • EZChrom Elite (3.3.3 or above)
  • MassHunter (B.02.01 sp1 or above)
  • Lab Advisor (B.01.03 or above)
• Local Control: Agilent Instant Pilot (G4208A) with firmware B.02.08 or above
• Communication Interfaces: CAN, RS-232C, APG Remote, optional external contact closures

Safety and Maintenance

• Leak Detection: Integrated leak sensors with safe handling mechanisms
• Diagnostics: Agilent LabAdvisor for error detection and performance monitoring
• GLP Features: Early maintenance feedback (EMF) for tracking instrument usage
• Housing: Recyclable materials with low-voltage maintenance zones

Additional Features

• Thermostatted Autosampler Option: Ensures precise temperature control for sample trays
• Needle Wash Station: Reduces carryover through external needle cleaning
• Compatibility: Works with various vial and plate formats, enabling flexibility in sample handling.