Agilent 1260 Infinity HPLC Fraction Collector G1364C (Refurbished)

The Agilent Technologies G1364C 1260 Fraction Collector is an advanced analytical-scale fraction collector designed for precise sample collection in liquid chromatography (LC) applications. Built for high-performance liquid chromatography (HPLC) and preparative workflows, this device ensures accurate fractionation based on time, peak detection, or external trigger mechanisms. The G1364C fraction collector is ideal for laboratories requiring precise fraction handling at flow rates below 10 mL/min, with modifications available for higher flow rates.

Equipped with an intuitive user interface and multiple configuration options, the Agilent 1260 Infinity Fraction Collector enables researchers to collect purified compounds efficiently while maintaining sample integrity. The collector is compatible with various trays, vials, well plates, and external containers, offering flexibility for diverse analytical applications. It features a compact design that integrates seamlessly with Agilent's LC systems, optimizing space and efficiency.

Technical Specification

General Specifications

• Model: Agilent G1364C 1260 Infinity Analytical-Scale Fraction Collector
• Application: Analytical-scale fraction collection in HPLC systems
• Flow Rate Compatibility: <10 mL/min (modifiable for higher flow rates)
• Fraction Collection Modes:
  • Time slices
  • Peak-based collection (Threshold, Up/Down Slope)
  • Combination of time and peak triggering
  • Manual trigger (supported with Agilent Instant Pilot G4208A)
• Supported Detectors for Fraction Triggering:
  • Agilent 1260 Infinity Diode Array Detectors (DAD)
  • Multi-Wavelength Detectors (MWD)
  • Variable Wavelength Detectors (VWD)
  • Fluorescence Detectors (FLD)
  • Agilent LC-MSD Mass Spectrometers
  • Universal Interface Box for third-party detectors

Fraction Collection Capacity & Trays

• Supported Trays:
  • 4 x well-plates (full tray for deep well plates)
  • 2 x well-plates with 10 x 2 mL vials
  • 100 x 2 mL vials (standard tray)
  • 3 x 40 x 2 mL vials (half trays)
  • 3 x 40 funnels for external collection
  • 3 x 15 x 6 mL vials (half trays)
  • Full tray with test tubes (30 mm OD, max. height 48 mm, ~20 mL/tube)
  • Installed trays are auto-detected by the system
• Maximum Tube/Plate Height: 48 mm (extendable to 75 mm with short needle assembly)
• Maximum Tube Volume: ~20 mL (with standard test tubes); unlimited with external funnels

Operating Modes & Features

• Discrete Fractions: Flow is diverted to waste between collections
• Continuous Flow: Available for well-plate applications, minimizing sample loss
• Needle Positioning Modes:
  • Above Location: Deposits sample above the collection vessel
  • Into Location: Needle penetrates capped vials or well plates
  • Droplet Setup Mode: Enables precise droplet formation and collection
• Delay Calibration: Internal delay volume compensation with an absorbance-based Flow Delay Sensor (FDS)
• Integrated Safety Features:
  • Leak detection and safe leak handling
  • Error detection and system alerts
  • Exhaust fan for vapor extraction

Diverter Valve & Delay Volumes

• Diverter Valve:
  • 3/2 low-volume diverter valve (~15 µL internal volume)
  • Switching time <100 ms
  • Maximum pressure: 6 bar
• Delay Volumes:
  • Inlet to diverter valve: ~50 µL (depends on tubing length)
  • Diverter valve to needle: ~10 µL
  • Needle internal volume: ~4 µL

Interfaces & Connectivity

• Communication Interfaces:
  • Controller-Area Network (CAN)
  • RS232C (optional)
  • APG-Remote for start/stop signal integration
  • Optional LAN or external contact interfaces
  • CAN-DC-Out for external device operation (e.g., valve control)
• Software Compatibility:
  • Agilent ChemStation
  • Agilent Lab Advisor
  • Agilent Instant Pilot (G4208A)
  • OpenLab CDS

Physical & Environmental Specifications

• Dimensions (H x W x D): 200 x 345 x 440 mm
• Weight: 13.5 kg (29.8 lbs)
• Power Requirements: 100-240 VAC, 50/60 Hz
• Operating Temperature: 4°C to 45°C
• Humidity: <95% (non-condensing)
• Cooling Option: Available with an external Agilent G1330B module

Compliance & Safety

• Safety Standards: IEC, CSA, UL certified
• Leak Detection: Integrated leak sensor
• Vapor Management: Built-in exhaust fan for fume extraction
• Regulatory Compliance: Meets GLP/GMP standards for traceability

The Agilent G1364C 1260 Infinity Fraction Collector is a versatile, high-precision solution for fraction collection in analytical-scale LC applications. With advanced collection modes, flexible configuration options, and seamless integration with Agilent's chromatography systems, it offers an efficient and reliable workflow for researchers and industrial applications alike. Its small footprint, automated operation, and intelligent delay volume calibration ensure optimal performance in demanding laboratory environments.