Agilent Technologies 1290 Infinity / AdvanceBio 6545XT LC-Q-TOF (Refurbished)

Agilent 1290 Infinity II LC + AdvanceBio 6545XT LC/Q-TOF

High-Resolution LC/MS Platform for Comprehensive Biomolecular Analysis

System Overview

This advanced LC/Q-TOF setup integrates the high-speed, high-pressure capabilities of the Agilent 1290 Infinity II LC with the biologics-optimized AdvanceBio 6545XT LC/Q-TOF mass spectrometer. It delivers fast, high-resolution separations and accurate mass detection, ideal for detailed structural and quantitative analysis of proteins, peptides, glycoforms, and other large biomolecules.

Included Modules:

• G7120A – 1290 Infinity II High-Speed Pump
• G7167B – High-Capacity Multisampler
• G7116B – Multicolumn Thermostat with integrated columnswitching valve
• G6549A – AdvanceBio 6545XT LC/Q-TOF MS
• Software Licenses – MassHunter and data analysis SW

Key Features & Benefits

• High-Speed Pump (G7120A)
  Delivers up to 1300 bar and 5 mL/min flow with active damping and smart stroke volume adaptation for smooth solvent delivery
• Multisampler (G7167B)
  Flexible vial/plate compatibility, optional cooling, low carryover, and scalable throughput for high sample volumes
• Multicolumn Thermostat (G7116B)
  Dual-zone Peltier-based temperature control (4–110 °C), support for up to 8 columns, and automated column switching for method flexibility
• AdvanceBio 6545XT LC/Q-TOF (G6549A)
  High-resolution, accurate-mass TOF detector optimized for biopharma workflows including intact protein analysis, peptide mapping, and glycan profiling.
• Integrated Software Suite
  MassHunter and other softwares provide intuitive control, advanced quantitation, and spectral interpretation for both routine and research workflows.

Key Specifications (Selected)

• G7120A Pump: 0.001–5 mL/min; ≤1300 bar; ±1% accuracy; high-pressure gradient capability
• G7167B Multisampler: Supports vials/MTP; cooled tray optional; LAN/ICF control; low carryover
• G7116B Thermostat: 4–110 °C; ±0.03 °C stability; cluster of up to 8 columns
• G6549A Q-TOF: High-res LC/MS; optimized for biologics and proteomics applications

Applications

• Proteomics, glycomics, metabolomics, biotherapeutics
• Intact protein profiling, peptide mapping, glycan analysis
• Post-translational modification studies and biosimilar characterization
• Degradation and impurity analysis in drug development