Agilent Technologies 1290 Infinity UHPLC Binary Pump (G4220A) (Refurbished)

The Agilent G4220A Binary Pump is a high-performance solvent delivery module designed for UHPLC applications within the Agilent 1290 Infinity LC system. It delivers exceptional pressure stability, low delay volumes, and precise gradient formation—ideal for fast, high-resolution separations using narrow-bore columns.

Key Features

• High-pressure capability up to 1200 bar, supporting UHPLC and demanding gradient applications
• Binary high-pressure mixing design for precise and reproducible gradients
• Two dual-piston pumps in series for low pulsation and high flow stability
• Flow range from 0.001 to 2.0 mL/min with 300 pL resolution
• Integrated degasser with two channels (1.5 mL internal volume each) for optimal solvent stability
• Optional active seal wash to extend seal life when using buffer-rich solvents
• Jet Weaver mixer with ultra-low delay volume (<45 µL with V35; <75 µL with V100) for fast gradient response
• Solvent selection valve (SSV) enables up to four solvent inlets for method flexibility
• Fast defill and smooth motion control to reduce pressure spikes and component wear

Specifications

• Flow rate range: 0.001 – 2.000 mL/min
• Flow precision: ≤ 0.07 % RSD or ≤ 0.005 min SD
• Flow accuracy: ±1% or 10 µL/min (whichever is greater)
• Pressure range: 0 – 1200 bar
• Pressure ripple: <1% or <5 bar (whichever is greater)
• Gradient type: High-pressure binary mixing
• Gradient accuracy: ±0.35% (5–95% range, 0.2–5.0 mL/min)
• Delay volume (Jet Weaver V35): <45 µL
• Delay volume (Jet Weaver V100): <75 µL
• Solvent channels: 2 (up to 4 solvents via SSV)
• Degassing unit: Integrated, 2 channels, 1.5 mL each
• Control software: Agilent ChemStation, OpenLab, MassHunter

Applications

• High-speed, high-resolution LC and LC/MS separations
• Ultra-fast gradient methods
• Bio/pharma, environmental, food, clinical, and small molecule workflows