Agilent Electrospray Ionization (ESI) Source for LCMS, G1948B (Refurbished)

The Agilent G1948B Electrospray Ionization (ESI) Source is a robust and reliable ion source designed for efficient ion generation in LC/MS systems. It supports soft ionization of polar and thermally labile compounds, making it ideal for a wide range of applications in pharmaceutical, environmental, biochemical, and food analysis.

Key Features

• Proven ESI technology for efficient ionization of polar, non-volatile, and thermally labile molecules
• Compatible with a wide range of Agilent LC/MS systems (e.g., 6100, 6200, 6400 Series)
• Produces high sensitivity and stable ion signals across diverse compound classes
• Soft ionization minimizes fragmentation, ideal for molecular weight determination
• Supports both positive and negative ion modes
• Adjustable nebulizer and drying gas parameters for method flexibility
• Easy maintenance and quick removal for cleaning or switching ion sources
• Ideal for LC/MS workflows in pharmaceutical R&D, clinical research, metabolomics, and food safety

Technical Specifications

• Ionization type: Electrospray Ionization (ESI)
• Operating modes: Positive and negative ion polarity
• Spray configuration: Coaxial nebulization with heated drying gas
• Gas requirements:
  – Nebulizer gas (N₂): Typically 20–60 psi
  – Drying gas (N₂): Flow rate adjustable, up to ~13 L/min
  – Temperature range: Adjustable, up to 350 °C (typical)
• Capillary voltage: Adjustable (commonly +3000 to +5000 V)
• Compatibility: Agilent single quadrupole, triple quadrupole, Q-TOF, and TOF LC/MS instruments
• Applications: Small molecules, peptides, metabolites, drugs, environmental contaminants