Waters Xevo G2-S QTOF Mass Spectrometer (Refurbished)

The Xevo® G2-S QTOF is a high-performance quadrupole time-of-flight mass spectrometer engineered for advanced qualitative and quantitative workflows. Featuring Waters’ StepWave™ ion optics, QuanTof™ technology, and intelligent data acquisition, the Xevo G2-S delivers exceptional sensitivity, resolution, dynamic range, and mass accuracy for complex applications in pharmaceutical R&D, biopharma characterization, metabolomics, proteomics, food safety, forensics, and environmental analysis.

Its robust design, fast polarity switching, and compatibility with UPLC® systems make it ideal for multi-purpose laboratories requiring high productivity and high-quality spectral information.

Key Features

• High-resolution QTOF platform with accurate mass capability
• StepWave™ ion guide for enhanced sensitivity and transmission
• QuanTof™ technology delivering high resolution and exceptional dynamic range
• LockSpray™ for real-time mass correction and excellent mass accuracy
• Fast polarity switching for comprehensive screening workflows
• Ideal for screening, structural elucidation, quantitation, and intact mass analysis
• Supports MSE, HDMSE (ion mobility model-dependent), and data-independent acquisition
• Seamless integration with ACQUITY UPLC® systems
• Controlled through UNIFI or MassLynx software platforms

Typical Technical Specifications

• Mass range: typically m/z 20–80,000
• Resolving power: up to ~40,000 FWHM
• Mass accuracy: < 1–2 ppm with LockSpray™
• Sensitivity: low-femtogram detection (compound-dependent)
• Dynamic range: 5–6 orders of magnitude
• Scan speed: up to 20–30 spectra/sec
• Polarity switching: < 20 ms
• Ionization sources: ESI, APCI, APPI, ASAP, UniSpray (optional)
• Software: MassLynx®, UNIFI®

Applications

• Metabolomics & lipidomics
• Proteomics (peptides, intact proteins)
• Small-molecule identification & quantitation
• Impurity profiling, structure elucidation
• Food safety, forensic toxicology
• Environmental monitoring