Next Generation Solutions for Oligonucleotide Analysis, Seattle, WA
Synthetic oligonucleotide therapeutics, such as antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs), require thorough analysis to establish purity, identity, and quality. As sequence length, chemical modifications, and regulatory expectations increase, so does the need for robust, reliable analytical methods.
This seminar highlights complete workflows from Waters Corporation featuring next generation instruments, consumables and software optimized specifically for synthetic oligonucleotide analysis. Explore proven approaches for impurity profiling, method development, scalable purification, and streamlined data analysis to confidently support development and quality workflows.
Join us for a lab demo showcasing how to automate your sample prep with Andrew+ pipetting robot and synthetic oligonucleotide separations and impurity detection. using Waters LC-MS systems.
Enjoy lunch, meet fellow scientists, and get your questions answered live by Waters experts.
📍Hilton Bellevue Hotel, 300 112th Avenue SE, Bellevue, WA 98004
AGENDA
- Fundamentals of Ion-Pairing Reverse Phase Separation of Oligonucleotides - Introduction to New 1mm I.D microflow column solutions for improved resolution and sensitivity
- Orthogonal techniques (HILIC, AEX, SEC) for oligonucleotide comprehensive profiling and regulatory confidence
- Sequence to Impurities: In-depth Oligonucleotide Characterization Using Next-Generation Multi-Reflecting TOF Mass Spectrometry
- High-throughput identity and impurity screening of synthetic oligonucleotide analysis using the BioAccord LC-MS System
LAB DEMO:
- Learn how to automate routine pipetting steps to improve reproducibility and throughput in synthetic oligo workflows.
- LC–MS: BioAccord demonstration of synthetic oligonucleotide separations and impurity detection.
Don’t miss this opportunity to stay ahead in science behind oligonucleotide analysis!
