SFC Europe 2025

The Green Chemistry Group was founded in 2007 as a nonprofit organization dedicated to the advancement of SFC and environmentally sustainable chemical research and development worldwide. We organized the first International Conference on Packed Column SFC, in 2008 in Pittsburgh, PA

Since then, we have hosted an annual SFC conference, alternating between the U.S. and Europe, and starting in 2015 added Asia. Each conference now attracts 150-200 scientists, from around the globe and spanning many industries, who use or are considering SFC as a green technology.

These scientific conferences feature:

• Keynote addresses
• Oral and poster presentations
• Exhibition by the industry leading suppliers of SFC equipment and services.
• Workshops
• An exhibition of the latest technologies and applications in supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE)
• A one-day short course prior to each conference that focuses on fundamentals and advances in SFC. Additional information on the short course can be found at “add link to new page describing short course”.

Registration

👉Registration

Registration fees

• Academic Scientist: $450.00
• Industry Scientist: $650.00
• Short Course: $350.00

Poster Abstract Submission

• Submit Poster Abstract HERE

• Submission Deadline: August 15, 2025

Programme

Speakers

Dr. Takeshi Bamba

• Dr. Takeshi Bamba is a professor at Division of Metabolomics, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, Japan. He has completed his Ph.D. from Osaka University. He has also worked as a chairman of Japan Society for SFC. His research revolves around an analytical science approach to metabolomics, focusing particularly on supercritical fluid technologies such as SFC and SFE. He has published more than 200 articles in scientific journals/books. 

Julie Herniman

• Julie Herniman leads the School of Chemistry and Chemical Engineering multi-user chromatography and mass spectrometry facilities at the University of Southampton in the UK. She specialises in the coupling of mass spectrometry to various forms of chromatography (GC, LC and SFC). Her research primarily focuses on the applications of SFC-MS to address problems in areas such as petrochemistry and renewable fuels, agrochemicals and formulated products, polymeric excipients and identification of biomarkers for the early detection of pressure ulcers. 

Jennifer Kingston

• Jennifer Kingston is a preparative chromatographer with extensive experience of achiral and chiral separations within drug discovery settings. During her career, she has successfully established preparative SFC facilities at Merck, Sharp and Dohme, Novartis and more recently at AstraZeneca in Cambridge, UK. Jennifer has a keen interest in extending the use of SFC within the pharmaceutical industry and promoting efficiency via automation and improvements in chromatographic methodologies. Jennifer is currently Director of Separation Science at AstraZeneca in Cambridge, UK. 

Lucie Nováková

• Lucie Nováková has been a Full Professor in Analytical Chemistry at the Charles University, Faculty of Pharmacy in Hradec Králové, Department of Analytical Chemistry, the Czech Republic since 2019. Her research is oriented towards separation techniques, namely ultra-high performance liquid chromatography, supercritical fluid chromatography, and their coupling to mass spectrometry. She is involved in a broad scope of research projects focused on pharmaceutical analysis, doping control, plant analysis, and bioanalytical methods. An important part of her research also lies in the sample preparation step, where the focus is put on the current trends enabling facilitation, miniaturization, and reduction of time and sample requirements. She extended her scientific experience during the fellowships at world-recognized universities, such as the University of Geneva and Vrije Universiteit Brussel, beyond others. She authored the book on HPLC theory and practice in Czech and in English and nine book chapters. She published over 155 peer-reviewed scientific articles and review papers with more than 5800 citations and an h-index of 42. She is also widely involved in teaching and education activities, such as HPLC and SFC training courses, seminars, and conferences. 

Prof. Dr. Maria Kristina Parr

• Maria Kristina Parr is working as professor for Pharmaceutical Analysis at Freie Universität Berlin, Germany, since 2012. The research focus of her group is mass spectrometric analysis hyphenated to different chromatographic separation techniques (GC-, LC- and SFC-MS(/MS)) with main focus on drug, supplement and bioanalysis as well as anti-doping research. Investigations in drug metabolism, determination of endogenous and xenobiotic compounds also considering drug-drug interactions play an important role in her research activities. Research activities in her team consider green and white analytical chemistry principles, quality management, and analytical quality by design. 

John Reilly

• Dr. Reilly is an Associate Director in the Department of Global Discovery Chemistry at Novartis Institute of Biomedical Sciences currently based in Basel, Switzerland. He currently leads the Separations team where there is a focus on providing purification and analytical characterization methodologies supporting a Chemistry unit with over 250 chemists. An advocate of knowledge exchange, Dr. Reilly has had global roles in Discovery and Development during his time at Novartis and previously with Eli Lilly. He completed both MSc. Birkbeck College in 1992 and Ph.D within Analytical Science Imperial College in 2002 after his initial BSc in Chemistry at Reading University in 1989. His research goals include the promotion of SFC new chromatographic characterization and purification methods and physicochemical affinity screens to investigate drug-like properties of molecules. Dr. Reilly has published >50 articles and has been a board member of The Chromatography Society and also has been on the editorial board of “Chromatography Today” and “American Journal of Modern Chromatography.” 

Short Courses

Short Course Registration Fee:  $350.00

This course will focus on fundamentals and advances in supercritical fluid chromatography (SFC) employing carbon dioxide-based mobile phases. Particular emphasis will be directed toward pharmaceuticals and other fields where SFC currently plays or will play a critical role such as lipidomics, specialty chemicals and polymers, biodiesel, foods and vitamins, natural products, and flavors/fragrances. Example applications in these areas will be used throughout the course as teaching illustrations. Attendees will gain the following knowledge:

• Fundamentals of CO2-based mobile phases – why do SFC?
• Practical advantages of SFC & SFE over GC-based and HPLC-based separations and liquid-based extraction – speed, cost, selectivity, etc.
• An understanding of SFC instrumentation, how it has improved over the years, and differences between SFC and HPLC equipment
• Method development in analytical-scale SFC and preparative-scale SFC - special considerations for scale-up
• Fundamentals of chiral SFC separations
• How to choose stationary phases for achiral and chiral SFC separations
• Which mixtures are suitable for SFC, and which mixtures may not be suitable?
• The role of modifiers/entrainers and additives in SFC and SFE separations
• Options for detection in SFC, with special emphasis on SFC/MS
• What are the latest developments and what is the future of SFC?

Target Audience

Anyone currently using GC, HPLC or other chromatographic techniques for analysis and/or purification and interested in learning how SFC can increase efficiency while reducing costs, or how SFC could be implemented as a complementary, orthogonal technique, will find this course of interest. This includes academic and industrial separation scientists, process chemists, laboratory and R&D managers in the pharmaceutical, specialty chemicals and polymers, food, lipidomics, biodiesel, natural products, flavors/fragrances, materials and medical research industries. Actual experience or knowledge of SFC is not required. Some knowledge of chromatographic principles is desirable.   

Short Course Agenda

9:30 a.m. – Registration

10:00 a.m. – Introduction of Instructors and Course Orientation

10:10 a.m. – Introduction to Supercritical Fluids and SFC 

• West

11:10 a.m. – Instrumentation in Analytical-Scale SFC 

• Pinkston

11:40 a.m. – Method Development for Chiral Analytical SFC 

• Miller

12:30 p.m. – Lunch

1:10 p.m. – Method Development for Achiral SFC 

• West

2:10 p.m. – Preparative SFC 

• Miller

3:10 p.m. – Break

3:25 p.m. – Detection in Packed Column SFC 

• Pinkston

4:15 p.m. – Discussion, Q&A

4:30 p.m. – Adjourn

SFC 2025 Schedule

Sunday, October 5, Hotel Victoria, Basel 

9:30-10:00 SFC Short Course Registration 

10:00-4:30 SFC Short Course 

Monday, October 6, Roche, Basel 

8:00 Registration 

9:00 Welcome and Opening Remarks

• Larry Miller, Green Chemistry Group 

Session Chair: TBD 

9:05 Fueling the Future: Biodiesel and the need for SFC

• Julie Herniman, University of Southampton 

9:30 Complementarity of Chromatographic Techniques (mono- and bi-dimensional) Coupled with Very High-Resolution Mass Spectrometry for the Characterisation of Microalgal Bio-oils. 

• Melanie Mignot^1,2, Jason Devaux¹, Carlos Afonso¹, Guillaume Limousin¹, Sabine Heinisch³, ¹CARMeN, ²INSA Rouen Normandie, ³ISA Lyon 

9:50 Combination of SBSE with online SFE-SFC-MS system to Analyze Migrating Plastic Additives in Medical Solutions and Biological Matrices,

• Benjamin Caux^1,2, Clement De Saint Jores², Ramy Abou-Naccoul², Horie Shinnosuke³, Toshiyuki Yamashita³, Takeshi Bamba⁴, Caroline West¹, ¹Orleans University, ²Shimadzu France, ³Shimadzu Europa Gmbh, ⁴Kyushu University 

10:10 Exhibition/Coffee Break 

Session Chair: TBD 

11:00 One for All: A SFC-MS/MS Platform Method for the Analysis of Multiple Nitrosamines in Accordance with the Guidelines of Good Manufacturing Practice. 

• Andreas Zappe, Mijo Stanic, Alexander Schmidt, Chromicent GmbH 

11:20 Improving the Greenness of SFC Separations for The Analysis of Natural Samples. 

• Paola Donato, Cristian Reale, Giovanna Cafeo, Marina Russo, Luigi Mondello, University of Messina 

11:40 Advancements in Lipidome Analysis Technologies Based on Supercritical Fluid Chromatography/Mass Spectrometry. 

• Maria Kristina Parr, Freie Universität Berlin 

12:05 Lunch 

1:05 Break/Exhibition 

Session Chair: TBD 

1:20 Streamlined Virgin Olive Oil Authenticity Assay through Lipid Unsaponifiable Fraction Profiling by Supercritical Fluid Chromatography-Mass Spectrometry. 

• Juan F. Garcia Reyes, Irene Cano-Carrillo, Bienvenida Gilbert-Lopez, University de Jaen 

1:40 Vendor Workshop - Agilent Technologies 

2:05 Chiral Ultrahigh-Performance Supercritical Fluid Chromatography / Mass Spectrometry for Advanced Isomeric Profiling of Triacylglycerols in Vegetable Oils. 

• Marika Kalpio, Dilakshi Navoda Naotunna Palliya Guruge, Qizhu Zhao, Baoru Yang, University of Turku 

2:25 Chiral Separation of Triacylglycerols in Human Milk Fats by Supercritical Fluid Chromatography. 

• Dilakshi Navoa Naotunna Palliya Guruge, Marika Kalpio, Baoru Yang, University of Turku 

2:45 Exhibit/Poster Session/Coffee Break 

4:00 TBD, Lucie Nováková, Charles University 

4:25 Vendor Workshop, Buchi Corporation 

6:00 Cocktail Reception, Hotel Victoria, sponsored by Buchi Corporation 

Tuesday, October 7, Roche, Basel. 

8:00 Registration 

Session Chair: TBD 

8:30 Advancements in Lipidome Analysis Technologies Based on Supercritical Fluid Chromatography/Mass Spectrometry. 

• Takeshi Bamba, Kyushu University 

8:55 Supercritical Fluid Chromatography with Atmospheric Pressure Ionization Tandem Mass Spectrometry for Denovo Lipids Characterization and Metabolites Isomer Differentiation. 

• Gerard Hopfgartner, Patrick Mueller University of Geneva LSMS 

9:15 Vendor Workshop - Teledyne 

9:40 Exhibit/Poster Session/Coffee Break 

Session Chair: TBD 

10:40 LNP Component Analysis and Purification Using SFC-CAD: Method Optimization and Solute-Dependent Response. 

• Victor Spelling, AstraZeneca

11:00 SFC as One Enabling Technology for High Purity Lipids and Peptides – showcases from Corden Pharma Switzerland. 

• Markus Juza, Corden Pharma Switzerland 

11:20 Vendor Workshop - PIC Solution 

11:45 Semi-preparative On-Line Supercritical Fluid Extraction-Supercritical Fluid Chromatography for Solid-State Injection and Purification

• Quentin Gros¹, Yusuke Masuda², Yoshiyuki Watabe², Hidetoshi Terada², ¹Shimadzu Europa GmbH, ²Shimadzu Corporation 

12:05 Lunch 

Session Chair: TBD 

1:15 Rocket Into Chiral Space 

• John Reilly, Novartis 

1:40 An Automated and Continuous Flow Solvent Delivery System for Preparative SFC Lab Operations

• Christopher DeVore, Brian Edwards, Amanda Holloway, Aaron Haak, Neurocrine Biosciences 

2:00 Accelerating Achiral SFC Purification at AstraZeneca Using Automated Processing and Machine Learning-Based Chromatographic Modeling

• Jennifer Kingston, AstraZeneca 

2:25 How we Support Chemistry Departments with Our Various SFC Instrumentation from Different Vendors at Roche Innovation Center, Basel

• David Wechsler, Hoffman La Roche AG 

2:45 Autonomous Screening and Optimisation of Chiral SFC Separations Using a Bayesian Multi-Objective Algorithm

• Matthew Notley, AstraZeneca 

3:05 Quantify Epimerization Kinetics of Lead Toxicology Compounds via Supercritical Fluid Chromatography: Sample Preparation and Analysis in Biorelevant Media

• Mengling Wong, Huy Nguyen, Alexandria Adams, Genentech 

3:25 Best Poster Awards Presentation, Invitation to SFC 2026 Japan and SFC 2026 Europe, Closing Remarks. 

• David Pinkston, Green Chemistry Group

General Info

Venue

Roche Tower (Building 1)
Grenzacherstrasse 124
Basel, 4070
Switzerland

Hotel

Hotel Victoria
Centralbahnplatz 3–4
4002 Basel