Thermo Fisher Scientific at HUPO 2025

Join us at the HUPO 2025 World Congress in Toronto, Canada to gather with leading researchers, and experts to learn more about mass spectrometry for proteomics, structural biology, and translational research. Stop by booth 501 during exhibit hours to connect and share insights!

Attend one of our seminars throughout the event and discover how Thermo Fisher Scientific is leading the industry.

Seminars

Advances in single cell proteomics, spatial proteomics and phosphoproteomics to enable comprehensive system profiling

Monday, November 10, 2025 | 12:15 - 1:15 p.m. EST

• Jun Qun (SUNY Buffalo)
• Jereon Krijgsveld (German Cancer Research Center (DKFZ), Helmholtz Association)
• Ugo Dionne (Lunenfeld-Tanenbaum Research Institute, Toronto)

Advances in chemoproteomics, immunopeptidomics and interactomics to enhance discovery and targeted profiling

Tuesday, November 11, 2025 | 8:00 - 9:00 a.m. EST

• Craig Braun (IQ Proteomics)
• Pouya Faridi (Monash University)
• Lan Huang (University of California, Irvine)

Beyond discovery: Making biomarkers matter

Wednesday, November 12, 2025 | 12:15 - 1:15 p.m. EST

• Sebastian Winter (ions.bio)
• Jennifer Van Eyk (Cedars-Sinai Medical Center)
• Phil Robinson (Children’s Medical Research Institute)

Technical presence

Unveiling the human molecular landscape: Integrated Omics in Translational research

Sunday, November 9, 2025 | 10:15 - 11:45 a.m.

Moderators:

• Khatereh Motamedchaboki, Sr Manager, Business Development, Thermo Fisher Scientific
• Yue Xuan, Sr Business Development Manager, Thermo Fisher Scientific
  Dr. Thomas P. Conrads, Inova Health System, Virginia, USA

Proteogenomics in precision oncology

• Dr. Thomas P. Conrads (Inova Health System, Virginia, USA)

Advancing precision medicine with Integrated Multi-Omics

• Dr. Sandra Goetze (ETH Zurich, Proteomics Platform D-HEST, Zurich, Switzerland)

Enabling discoveries through Proteogenomic Integration: From variant impact to cancer epitopes

• Dr. Bing Zhang (Baylor College of Medicine, Houston, Texas, USA)

Proteogenomics-driven precision oncology: Pancreatic ductal adenocarcinoma subtype identification technology & basket trials

• Dr. Sang-Won Lee (Korea University, Seoul, Korea)

Posters

Poster session 1

Monday, November 10, 2025 | 1:15 - 3:15 p.m.

• Unlocking Precision Oncology: Harnessing Proteogenomics for Unmatched Insights from Big Data
• PTM Analysis with EThcD on a Modified Orbitrap Exploris Instrument
• nDIA analysis on the Orbitrap Astral combined with PTMScan enrichment provides an expanded global view of protein post translational modifications
• High Select Fe-NTA Magnetic Beads for Phosphopeptide Enrichment
• Discovering biomarkers in plasma through a highly multiplexed targeted proteomics assay utilizing the Stellar mass spectrometer and adaptive RT
• A Hybrid-DIA Approach for Simultaneous Targeted and Untargeted Analysis Using an Orbitrap Tribrid System
• Comprehensive and High-Throughput Plasma Proteome Profiling for Biomarker
• Discovery using a modified Orbitrap Astral Mass Spectrometer
• High-Throughput Plasma Proteomics Reveals Biological Insights Using PreOmics
• Sample Preparation Kits with the Thermo Scientific Orbitrap Astral Mass Spectrometer
• Scalable Plasma Proteomics Workflow Reveals Disease Insights Using the Seer Proteograph Workflow and the Thermo Scientific Orbitrap Astral Mass Spectrometer
• Leveraging Hybrid-DIA data acquisition modalities for comprehensive plasma proteomics analysis on modified Orbitrap Hybrid and modified Orbitrap Astral Mass Spectrometers
• Improved reproducibility and robustness for plasma proteomics on Orbitrap Astral MS using a novel automated ion source and separation cartridge
• Improved precision and accuracy in quantitative proteomics using a novel ion source on a modified Orbitrap Hybrid mass spectrometer
• Improved accuracy and identification in label-free quantitative proteomics using a novel ion source and separation cartridge with integrated replaceable emitters
• Enhancing the resolving power on a modified Orbitrap Astral mass spectrometer for TMT35plex applications
• Enhancing Glycopeptide Identification: Comparative Analysis of Orbitrap Mass Spectrometers
• Improved Quantitation in Proteomics Analysis Using Stellar Mass Spectrometry for High-Throughput Studies
• Enhancing Glycopeptide Identification: Comparative Analysis of Orbitrap Mass Spectrometers
• Leveraging Adaptive RT on Orbitrap Ascend MultiOmics Tribrid Mass Spectrometer for Improved Sensitivity and Throughput in Targeted and Hybrid Workflows

Poster session 2

Tuesday, November 11, 2025 | 1:15 - 3:15 p.m.

• High-Throughput Molecular Glue Screening via Native Mass Spectrometry and Cryo-EM Analysis
• The Secret Life of Proteins and Drugs Through the Lens of Proteome Thermal Stability
• Evaluation of a novel, automated ion source for label-free peptide quantitation and global proteomics analysis
• Evaluation of OptiSpray Technology and the Orbitrap Astral Zoom Mass Spectrometer for Proteomics Applications
• Evaluation of prioritized peptide acquisition for multiplexed single-cell proteomics on an Orbitrap Astral Zoom mass spectrometer
• A novel tandem LC workflow for maximizing mass spectrometer utilization
• Low-input and single-cell proteomics sample analysis with a novel ion source and cartridge column on a Tribrid Mass Spectrometer
• Alternative fragmentation is not enough for Top-down MS and intact proteoform characterization
• Expanding the Landscape of Biomarker Discovery in a Multi-cancer Cohort

Poster session 3

Wednesday, November 12, 2025 | 1:15 - 3:15 p.m.

• Cutting-Edge Targeted Pathway Analysis: Advancing Functional Proteogenomics in Cancer Cells
• MS-cleavable Cross-linking analysis on modified Orbitrap Astral mass spectrometer
• Innovative data-independent acquisition (DIA) workflows for protein–nucleic acid interactions in living cells
• Enhanced immunopeptidome characterization with the high-sensitivity and accuracy of the modified Orbitrap Astral Mass Spectrometer
• Data-Independent acquisition for comprehensive immunopeptidome profiling on a modified Orbitrap Astral mass spectrometer
• Multiple target monitoring enables high throughput, large scale targeted assays for biomarker discovery and verification
• Expert Review - PRM Conductor - processing large-scale Stellar data
• Synchronous Precursor Selection of Light/Heavy Peptides on the MS-Level using the Stellar Mass Spectrometer
• Comprehensive Immunopeptidome Profiling with Optimized Enrichment and MS Analysis
• Capture Scheduled Retention Time Window Shift in Large Scale of Peptide Quantitation Using a Modified OrbitrapTM Hybrid Mass Spectrometer
• Hybrid-DIA on the modified Orbitrap Exploris 480 Mass Spectrometer: Bridging Global Depth and Targeted Sensitivity for Proteomic Analysis
• Higher Order Structure Characterization of ADCs using Hydrogen-deuterium Exchange Mass Spectrometry (HDX-MS)
• High-Throughput Protein Profiling of FFPE and Fresh-Frozen Samples Using BeatBox and Vanquish Neo Coupled with Orbitrap Astral

Corporate poster

• AAV6 VP3-Only Capsids for Standardization in Ion-Exchange Chromatography, Native Mass Spectrometry, and Charge Detection Mass Spectrometry
• Evaluation of Robustness and Reproducibility of the OptiSpray Ion Source and Cartridge Columns
• Evaluation Of the OptiSpray Ion Source And Cartridges With Integrated Replaceable Emitters For Proteomics Data Acquisition
• Experimental Characterization of Automated Emitter Position Optimization Strategies for a New Low-Flow Ion Source and Cartridge

Oral presentation

Wednesday, November 12, 2025 | 10:20 - 11:50 a.m.

• Experimental Characterization of Automated Emitter Position Optimization Strategies for a New Low-Flow Ion Source and Cartridge