Principal Scientist, Purification PD

Just – Evotec Biologics, wholly-owned by Evotec SE, is a unique platform company that integrates the design, engineering, development, and manufacture of biologics. With deep experience in the fields of protein, process and manufacturing sciences, the Just team came together to solve the scientific and technical hurdles that block access to life-changing protein therapeutics; from the design of therapeutic molecules to the design of the manufacturing plants used to produce them. Just's focus is to create access and value for a global market through scientific and technological innovation.

Do you possess expertise in chromatography and filtration technology and operations?

Are you experienced in high throughput chromatography screening, chromatography mechanistic modeling, multicolumn chromatography, and/or process modelling, experienced managing a small growing team?

We're looking for the perfect candidate to join our team. If this description fits you, we'd love to hear from you!

PRINCIPAL SCIENTIST, PURIFICATION PD

Role and Responsibilities

Just – Evotec Biologics’ Purification Process Development group is seeking an enthusiastic and hardworking team member who is passionate about expanding worldwide access to biotherapeutics through the advancement of continuous bioprocessing technology. This person will join a fast-paced, collaborative, and multidisciplinary team to support purification process development at the bench and pilot scale for the advancement of low-cost biotherapeutics manufacturing. Process design at Just-Evotec means exposure to innovative technologies like high throughput automated robotic screening and continuous processing technologies for a first-of-its-kind flexible and reconfigurable end-to-end continuous manufacturing facility.

Key Responsibilities

Join the dynamic team at Just – Evotec Biologics, working to advance global access to biotherapeutics through continuous bioprocessing technology.

This role will encompass a range of exciting responsibilities, including:

• Leading a diverse team of scientists involved in purification process development, characterization, and validation, including technology transfer to cGMP manufacturing for hybrid and continuous processes.

• Serving as an internal technical resource for cGMP manufacturing and process design as well as a subject matter expert for external clients and partners.
  Collaborating across the organization to accelerate clinical development timelines and reduce costs.

• Effectively communicating scientific information and experimental results to various stakeholders, both internal and external.

• Authoring SOPs, reports, and slides to summarize and interpret experimental data.

• Conducting risk assessment and authoring protocols for late-phase process robustness and process characterization.

• Designing, executing, and analyzing statistically designed experiments (DOE) for commercialization of late-phase programs.

• Collaborating with vendors and manufacturers to develop, order, and troubleshoot equipment prototypes.

• Mentoring, training, and supervising staff and interns.

• Driving technology development for process intensification and continuous manufacturing to reduce costs and footprint.

Education and Experience

• BS/MS in Engineering, Biochemistry, Biology, or related field with 12+ years of experience or Ph.D. in Engineering, Biochemistry, Biology, or related field with 8+ years of experience.

• Expertise in purification technology and process development, transfer to cGMP manufacturing plants, and authoring CMC sections of regulatory filings.

• Experience with commercial process development, process characterization, and validation.

• Expertise in design of experiments (DOE) and statistical analysis with relevant statistical software.

• Experience in training, mentoring, and supervising team members as well as leading development teams for external client projects and collaborations and internal technology development initiatives.

• Experience with high throughput process development systems is a plus.

Essential*

• Proficiency in data analysis using tools such as JMP, R, or Python.

• General understanding of cell biology, fluid dynamics, and protein chemistry, as well as knowledge in other functional areas (upstream and analytical sciences).

• Experience working in a cGMP or clean room setting (GMP knowledge is helpful).

• Strong written and verbal communication skills, including client and multi-site communication.

• Familiarity with common software packages (e.g., Microsoft Office).

• A curious, creative, and proactive mindset, with a strong ability to work both independently and as part of a team to advance scientific processes and technology.

Additional Benefits

We offer a competitive salary and a fantastic benefits package and annual bonuses, plus, expenses covered where travelling is required.

The base pay range for this position at commencement of employment is expected to be $140,000 to $170,000; Base salary offered may vary depending on individual’s skills, experience and competitive market value. Additional total rewards include discretionary annual bonus, comprehensive benefits to include Medical, Dental and Vision, short-term and long-term disability, company paid basic life insurance, 401k company match, flexible work, generous paid time off and paid holiday, wellness and transportation benefits.

Evotec (US) Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, gender, age, disability, genetic information, gender expression, gender identity, national origin, religion, sexual orientation, or veteran status.