Postdoctoral fellow in computational mass spectrometry

IOCB Prague is a leading research institution under the umbrella of the Czech Academy of Sciences. Our mission is basic research at the interface of chemical and biological sciences and translation of results from basic research into applications and commercial assets.

Postdoctoral fellow in computational mass spectrometry

GROUP Tomáš Pluskal Group Biochemistry of Plant Specialized Metabolites

Tomáš Pluskal Group at IOCB Prague combines cutting-edge experimental (e.g., LC-MS, metabolomics, RNA-seq) and computational (e.g., bioinformatics, molecular networking, machine learning) approaches to develop rapid, generally applicable workflows for the discovery and utilization of bioactive molecules derived from plants. We are looking for talented and motivated computational researchers to join our team.

The successful candidate for this position will be developing new tools and approaches for computational metabolomics, especially (but not limited to) using the popular mzmine framework for mass spectrometry data processing.

IOCB Prague is one of the leading research institutes in central Europe with a vibrant international environment and excellent equipment and core facilities located in modern buildings close to the Prague city center.

Relevant publications:

• Schmid, R., Heuckeroth, S., Korf, A. et al. Integrative analysis of multimodal mass spectrometry data in MZmine 3. Nat Biotechnol 41, 447–449 (2023)

• Heuckeroth, S., Damiani, T., Smirnov, A. et al. Reproducible mass spectrometry data processing and compound annotation in MZmine 3. Nat Protoc (2024)

• Bushuiev, R., Bushuiev, A., et al. Emergence of molecular structures from repository-scale self-supervised learning on tandem mass spectra. ChemRxiv (2024)

• Mutabdžija, L. et al. (2024). Studying Plant Specialized Metabolites Using Computational Metabolomics Strategies. In: Maghuly, F. (eds) Plant Functional Genomics. Methods in Molecular Biology, vol 2788. Humana, New York, NY.

Requirements

• PhD degree in the field of computer science, bioinformatics, or machine learning obtained no more than 5 years ago.

• Good track record of previous scientific publications and achievements.

• Fluency in spoken and written English.

• Passion for basic research and science

We offer

• Competitive salary

• 5 weeks of vacation + 4 days of personal leave

• Health insurance and full benefits package incl. contribution to pension, culture, and sport

• Lunch subsidy

• Financial support for parents with young children who return to work immediately after the maternity/parental leave

• Other IOCB employee benefits

Additional information

STARTING DATE

• negotiable

CONTRACT

• initial full-time fixed-term contract for one year, with the possibility of extension

How to apply

Please email your CV, a cover letter, and contact details of 2-3 references to Dr. Tomáš Pluskal: [email protected]