Associate Scientist, Late-Stage Formulation Sciences
AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development, and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.
Associate Scientist, Late-Stage Formulation Sciences
The Late-Stage Formulation Sciences (LSFS) Group is responsible for development of intended commercial formulations to advance AstraZeneca’s late stage biologics portfolio, and the life cycle management of commercialized products. The group plays an integral part in the design and development of patient centric drug products.
As a part of Biopharmaceutical Development, the Late-Stage Formulation Sciences group, within the department of Dosage Form Design and Development, is on a mission to develop extraordinary products through excellent science, forward-thinking execution, and compassion for patients and those who touch our products. We develop and characterize intended commercial formulations and finished dosage forms to deliver high quality biologics to the market for patients. We develop robust formulations, Drug Products, and product control strategies to ensure approval of marketing applications for product commercialization and launch.
What you’ll do
- Design and execute experiments for extractables and leachables studies as part of biologics formulation development.
- Exercise technical discretion and scientific rigor in experimental protocol design, data analysis, and results interpretation.
- Work with contract testing laboratories and contribute to implementation of extractables and leachables testing strategy.
- Participate in formulation development activities for late-stage assets.
- Present findings in departmental and inter-departmental meetings and prepare technical reports.
Education
- BS in Chemistry, Biochemistry, Pharmaceutical Sciences, Bioengineering or a related field with 0-2+ years of laboratory-based experience.
Required Skills
- Experience with small-molecule analytical techniques for detection, identification, quantitation, and characterization is a must.
- Hands-on experience with gas and liquid chromatography, and mass spectrometry is strongly preferred.
- High degree of self-motivation and drive for results are critical.
Desired Skills
- Experience with Drug Substance and Drug Product formulation risk assessments and characterization studies a plus.
- Experience with analytical method validation, formulation and biopharmaceutical development, characterization, control strategy, quality risk management, and/or CMC regulatory guidance and BLA filings is desired.
- Skills leading, planning, and executing complex projects on tight timelines are a plus.
When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of three days per week from the office. But that doesn't mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
