Principal Scientist

Novartis is an innovative medicines company. Every day, we work to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach more than 250 million people worldwide.

We are seeking a highly skilled analytical scientist with demonstrated experience in the implementation and use of chromatography systems for the separation and purification of small molecules. The selected individual will be responsible for the purification and characterization of synthetic molecules, including chiral, using reverse phase chromatography (RPC), supercritical fluid chromatography (SFC) and automation. Self-motivation, scientific curiosity, attention to detail, and strong communication skills are required.

The successful candidate will be an integral member of our drug discovery efforts, providing leadership and expertise to medicinal chemistry synthetic efforts by developing methods and conducting the separation and purification of organic molecules. This person will be expected to communicate effectively and work collaboratively with other scientists to develop innovative medicines. This role will impact our local discovery efforts and the global discovery portfolio through both leadership and bench-level contributions.

PRINCIPAL SCIENTIST

Your responsibilities:

• Separation and purification of small molecules including enantiomers by mass-directed reverse phase and supercritical fluid chromatography by ensuring that appropriate processes and infrastructure are in place. This includes setup, chromatographic method development, support, troubleshooting, and root cause error analysis of laboratory equipment.

• Collaborate with equipment vendors for new instrument research, purchasing, and set up as well as advancement of capabilities.

• Evaluate opportunities and when applicable, integrate new analytical technologies and software to improve efficiency, quality, and productivity.

• Design and implement new laboratory policies, methods, and procedures.

• Identify bottlenecks, and systematically evaluate and assess root causes of errors in the laboratory.

• Collaborate with IT and automation groups to develop and enhance the capabilities of the current infrastructure and investigate future capabilities to adjust to changing lab demands.

Diversity & Inclusion / EEO

We are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Accessibility and Reasonable Accommodations: Individuals in need of a reasonable accommodation due to a medical condition or disability for any part of the application process, or to perform the essential functions of a position, please let us know the nature of your request, your contact information and the job requisition number in your message:

Novartis: e-mail [email protected] or call +1 (877)395-2339
Sandoz: e-mail [email protected] or call: +1-609-422-4098

Role Requirements:

• PhD in chemistry or related field with at least 2 years of related experience OR an MS or BS/BA degree with at least 5 years of related experience.

• Strong background in analytical chemistry and separation science.

• Hands-on experience with operation and troubleshooting of analytical instruments, including HPLC, SFC and automation equipment.

• Strong computer skills, including familiarity with instrument control software.

• Experience with the principles of mass spectrometry and the operation of mass spectrometers.

Why Novartis?

Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us! Learn more

You’ll receive:

• You can find everything you need to know about our benefits and rewards in the Novartis Life Handbook

Commitment to Diversity & Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams’ representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Novartis Compensation and Benefit Summary:

• The pay range for this position at commencement of employment is expected to be between $112,800 and $169,200; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities.

• The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered.

• Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

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