Applications from the field of Clinical Research - page 73

Characterization of IgG1 monoclonal antibody (mAb) oxidation variants at intact, subunit and peptide levels

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research

Confident peptide mapping and disulfide bond analysis of an IgG2 monoclonal antibody

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Proteomics , Clinical Research

Evaluating BioAccord LC-MS System Performance for Deployment of a Compact, SmartMS-Enabled Biopharma Solution in Late Stage Development and QC Environment – Intact Mass Analysis

Applications

| 2020 | Waters

LC/TOF, LC/HRMS, LC/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS

Manufacturer

Waters

Industries

Clinical Research

Separation and Analysis of TCA Cycle Analytes by Mixed-Mode Chromatography Coupled with Mass Spectrometry

Applications

| 2020 | Waters

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Clinical Research

LipidQuan: A Rapid and Comprehensive Targeted Approach Investigating the Lipidome of Bladder Cancer Subjects

Applications

| 2020 | Waters

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Clinical Research, Lipidomics

Multiple Heart-cut 2D-LC/MS with UNIFI Informatics for Compliant Monitoring of Monoclonal Antibody Charge Variants

Applications

| 2020 | Waters

LC/MS, 2D-LC

Instrumentation

LC/MS, 2D-LC

Manufacturer

Waters

Industries

Clinical Research

Evaluation of Undifferentiated State of Human iPS Cells Using C2MAP™ Cell Culture Media Analysis Platform

Applications

| 2020 | Shimadzu

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Shimadzu

Industries

Clinical Research

Utilizing UPLC Separation to Enable the Analysis of 19 Steroid Hormones in Serum for Clinical Research

Applications

| 2020 | Waters

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Clinical Research

Rapid Identification of Major Metabolites of Gefitinib Using Ion Mobility Enabled MS (HDMSE) with the SYNAPT XS

Applications

| 2020 | Waters

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Metabolomics, Clinical Research

Comprehending COVID-19: Preliminary Examination of the SARS-CoV-2 Spike Protein by Peptide Mapping

Applications

| 2020 | Waters

LC/TOF, LC/HRMS, LC/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS

Manufacturer

Waters

Industries

Clinical Research