Applications from the field of Clinical Research - page 92

Studying protein-drug complexes under native conditions in the low nM range using MRMS

Applications

| 2020 | Bruker

LC/MS, LC/Ultra-HRMS

Instrumentation

LC/MS, LC/Ultra-HRMS

Manufacturer

Bruker

Industries

Clinical Research

Rapid Top-Down Analysis of the NISTmAb antibody

Others

| 2020 | Bruker

MALDI, LC/TOF, LC/MS

Instrumentation

MALDI, LC/TOF, LC/MS

Manufacturer

Bruker

Industries

Clinical Research

Ultra-fast LCMS analysis of Antiarrhythmic drugs in plasma

Posters

| 2020 | Shimadzu

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Shimadzu

Industries

Clinical Research

Incorporating CCS values to enable 4-dimensional annotation of metabolic features

Applications

| 2020 | Bruker

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Bruker timsTOF fleX - MALDI Guided SpatialOMx

Guides

| 2020 | Bruker

Ion Mobility, MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

Ion Mobility, MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Caution! MALDI-2 detects analyte classes never seen before

Others

| 2020 | Bruker

MALDI

Instrumentation

MALDI

Manufacturer

Bruker

Industries

Clinical Research

TIMS enabled quantification of small molecules in MALDI Imaging

Technical notes

| 2020 | Bruker

MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

MALDI, MS Imaging, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Clinical Research

Extracellular Flux Analysis and 13C Stable-Isotope Tracing Reveals Metabolic Changes in LPS-Stimulated Macrophages

Applications

| 2020 | Agilent Technologies

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies

Industries

Metabolomics, Clinical Research

A Fast Analytical LC/MS/MS Method for the Simultaneous Analysis of Barbiturates and 11-nor-9-carboxy-Δ9- tetrahydrocannabinol (THC-A) in Urine

Applications

| 2020 | Agilent Technologies

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Agilent Technologies

Industries

Forensics , Clinical Research

Quantification of drugs of abuse in human blood by TurboFlow chromatography coupled to tandem mass spectrometry for use in clinical research

Applications

| 2020 | Thermo Fisher Scientific

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research