Applications from the field of Pharma & Biopharma focused on LC/HRMS - page 1

High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system

Posters

| 2025 | Thermo Fisher Scientific (HPLC Symposium)

2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC

Instrumentation

2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling

Posters

| 2025 | Thermo Fisher Scientific (HPLC Symposium)

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Instrumentation

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides

Posters

| 2025 | Thermo Fisher Scientific (HPLC Symposium)

Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Instrumentation

Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods

Posters

| 2025 | Thermo Fisher Scientific (HPLC Symposium)

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Instrumentation

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies

Posters

| 2024 | Thermo Fisher Scientific (HPLC Symposium)

Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

A novel approach for multiple PQAs monitoring of mAbs from bioreactors using 2D-LC-MS

Posters

| 2024 | Thermo Fisher Scientific (HPLC Symposium)

2D-LC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

2D-LC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

LC/UV/HRMS-based impurity profiling and structure elucidation of phosphoramidite raw materials used for oligonucleotide synthesis

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Comprehensive extractables analysis using novel automated parallel extraction and concentration coupled with a multi-detector LC/UV/CAD/HRAM Orbitrap MS system

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

Sample Preparation, HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Sample Preparation, HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Myth busting: “You cannot sequence oligonucleotides over 20 to 30 nucleotides long by LCMS/MS” Learn how to routinely sequence 100 nt oligonucleotides

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Novel applications of multi-detector HPLC systems in pharmaceutical analysis

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC/SQ

Instrumentation

HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC/SQ

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma