Applications from the field of Pharma & Biopharma focused on LC/MS - page 39

Optimizing Mass Spectrometer Conditions to Accurately Determine Full/Empty AAV Ratios: A Sample Half-Full Approach

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Quantification of Glucagon-Like Peptide-1 Agonist Tirzepatide Using an Agilent 6495D Triple Quadrupole LC/MS System

Applications

| 2024 | Agilent Technologies

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Agilent Technologies

Industries

Pharma & Biopharma

Analysis of Oligonucleotides Using an Ion-Pairing-Free Reversed-Phase Method with TOF LC/MS

Applications

| 2024 | Agilent Technologies

HPLC, LC/MS, LC/TOF, LC/HRMS

Instrumentation

HPLC, LC/MS, LC/TOF, LC/HRMS

Manufacturer

Agilent Technologies

Industries

Pharma & Biopharma

Confident transformation site localization of PROTAC drug metabolites facilitated by multi-stage fragmentation LC-HRAM-MS

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

IMPROVED TISSUE HOMOGENIZATION AND SPE-BASED SAMPLE PREPARATIONS FOR THE QUANTITATIVE LC-MS ANALYSIS OF OLIGONUCLEOTIDE THERAPEUTICS

Posters

| 2024 | Waters (ASMS)

Sample Preparation, LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

Sample Preparation, LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Pharma & Biopharma

Applying UHPLC HRAM MS-MS/MS method to assess host cell protein clearance during the purification process development of therapeutic mAbs

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/MS, LC/MS/MS, LC/HRMS, LC/Orbitrap

Instrumentation

LC/MS, LC/MS/MS, LC/HRMS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma, Proteomics

Method considerations for therapeutic ASO RNA analysis. Adducts and insource impurity generation

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Complete Characterization of Trastuzumab Deruxtecan, a Cysteine-linked antibody drug conjugate, using high resolution accurate mass (HRAM) Mass Spectrometry

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Increased sensitivity and throughput for native intact mass analysis of mAb and ADCs using an online buffer exchange column

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, Consumables

Instrumentation

LC/HRMS, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, Consumables

Manufacturer

Thermo Fisher Scientific

Industries

Proteomics , Pharma & Biopharma

Imaged capillary isoelectric focusing – Mass Spectrometry (iCIEF- MS) online coupling for polatuzumab vedotin charge heterogeneity analysis using native MS

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma