Applications from the field of Pharma & Biopharma focused on LC/Orbitrap - page 5

Increased sensitivity and throughput for native intact mass analysis of mAb and ADCs using an online buffer exchange column

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, Consumables

Instrumentation

LC/HRMS, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, Consumables

Manufacturer

Thermo Fisher Scientific

Industries

Proteomics , Pharma & Biopharma

Imaged capillary isoelectric focusing – Mass Spectrometry (iCIEF- MS) online coupling for polatuzumab vedotin charge heterogeneity analysis using native MS

Posters

| 2024 | Thermo Fisher Scientific (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Increased sensitivity and throughput for native intact mass analysis using a NativePac OBE-1 SEC column and an Orbitrap Ascend Tribrid mass spectrometer

Technical notes

| 2024 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC columns, LC/Orbitrap, LC/MS/MS, Consumables

Instrumentation

LC/HRMS, LC/MS, LC columns, LC/Orbitrap, LC/MS/MS, Consumables

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Orbitrap Ascend BioPharma Tribrid mass spectrometer

Brochures and specifications

| 2024 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

In-depth characterization of monoclonal antibodies

Applications

| 2024 | Thermo Fisher Scientific

LC/Orbitrap, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/Orbitrap, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Detection and identification of isotope-labeled glutathionetrapped reactive drug metabolites

Technical notes

| 2024 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma, Clinical Research

Highly sensitive and robust LC-HRAM-MS method for simultaneous quantitation of sixteen nitrosamines in multiple drug products

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Confident and sensitive profiling of lipid nanoparticle raw materials and impurity identification using a LC/CAD/HRAM-MS method with inverse gradient

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Development of a systematic approach for improving tryptic digestion, recovery and chromatographic performance for mAb analysis

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Improved and universal inline electrochemical reduction and subunits LC-MS analysis of multiple classes of monoclonal antibodies

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma