Applications from the field of Pharma & Biopharma focused on LC/Orbitrap - page 6

Accurate and consistent analysis of poly(A) tails of mRNA therapeutics on a UHPLC-HRAM-MS platform

Applications

| 2024 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Detection and identification of isotope-labeled glutathionetrapped reactive drug metabolites

Technical notes

| 2024 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, Software

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma, Clinical Research

Highly sensitive and robust LC-HRAM-MS method for simultaneous quantitation of sixteen nitrosamines in multiple drug products

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Novel applications of multi-detector HPLC systems in pharmaceutical analysis

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC/SQ

Instrumentation

HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC/SQ

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Myth busting: “You cannot sequence oligonucleotides over 20 to 30 nucleotides long by LCMS/MS” Learn how to routinely sequence 100 nt oligonucleotides

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

LC/UV/HRMS-based impurity profiling and structure elucidation of phosphoramidite raw materials used for oligonucleotide synthesis

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Efficient and sensitive peptide mapping approach by μPAC columns with ultralow sample loading

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

Consumables, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC columns

Instrumentation

Consumables, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC columns

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Comprehensive extractables analysis using novel automated parallel extraction and concentration coupled with a multi-detector LC/UV/CAD/HRAM Orbitrap MS system

Posters

| 2023 | Thermo Fisher Scientific (HPLC Symposium)

Sample Preparation, HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Sample Preparation, HPLC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

LC/UV/HRAM MS-based impurity profiling and structure elucidation of phosphoramidite raw materials used for oligonucleotide synthesis

Applications

| 2023 | Thermo Fisher Scientific

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Development of a systematic approach for improving tryptic digestion, recovery and chromatographic performance for mAb analysis

Applications

| 2023 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma