Applications from the field of Pharma & Biopharma - page 16

Salt gradient analysis of Protein G using a 3 μm monodisperse SAX chromatography column

Applications
| 2023 | Thermo Fisher Scientific
HPLC, Consumables, LC columns
Instrumentation
HPLC, Consumables, LC columns
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Coupling ion exchange chromatography with mass spectrometry to characterize charge heterogeneity of mAbs under near-native conditions using a ProPac 3R SCX column

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS/MS, LC/MS, LC/Orbitrap, LC columns, Consumables
Instrumentation
LC/HRMS, LC/MS/MS, LC/MS, LC/Orbitrap, LC columns, Consumables
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Improved and universal inline electrochemical reduction and subunits LC-MS analysis of multiple classes of monoclonal antibodies

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Automated, compliance-ready, intact mass confirmation of modified oligonucleotides using an LC-MS platform

Applications
| 2023 | Thermo Fisher Scientific
LC/MS, LC/SQ
Instrumentation
LC/MS, LC/SQ
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Sensitive quantitation of antisense oligonucleotides in plasma using high-resolution, accurate-mass (HRAM) mass spectrometry

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Analysis of genotoxic impurities in pharmaceuticals

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Analysis of impurities in topiramate by HPLC with charged aerosol detection and a single quadrupole mass spectrometer

Applications
| 2023 | Thermo Fisher Scientific
HPLC, LC/MS, LC/SQ
Instrumentation
HPLC, LC/MS, LC/SQ
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Characterization of adeno-associated viral proteins proteoforms using a top-down MS approach on a UHPLC-Orbitrap Ascend Tribrid mass spectrometer

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma, Proteomics

Confident intact mass analysis of the tRNA isodecoders of phenylalanine by UHPLC-HRAM-MS and BioPharma Finder software

Applications
| 2023 | Thermo Fisher Scientific
Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
Software, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Confident and sensitive profiling of lipid nanoparticle raw materials and impurity identification using a LC/CAD/HRAM-MS method with inverse gradient

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Other projects
GCMS
ICPMS
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