Applications from the field of Pharma & Biopharma - page 51

A Xevo™ G3-based Workflow for Purity Determination, Intact Mass Measurement, and MS/MS Sequencing of Impurities Detected in Synthetic Oligonucleotides

Applications

| 2024 | Waters

LC/HRMS, LC/MS, LC/MS/MS, LC/TOF

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/TOF

Manufacturer

Waters

Industries

Pharma & Biopharma

Platform Ion Pairing RPLC Method for Oligonucleotides Using High Throughput 20 mm Length Columns

Applications

| 2024 | Waters

Consumables, LC columns, HPLC

Instrumentation

Consumables, LC columns, HPLC

Manufacturer

Waters

Industries

Pharma & Biopharma

Tunable Digestions of RNA Using RapiZyme™ RNases to Confirm Sequence and Map Modifications

Applications

| 2024 | Waters

Consumables, Sample Preparation, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF, Standards and chemicals

Instrumentation

Consumables, Sample Preparation, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF, Standards and chemicals

Manufacturer

Waters

Industries

Pharma & Biopharma

RNA Digestion Product Mapping Using an Integrated UPLC-MS and Informatics Workflow

Applications

| 2024 | Waters

Consumables, Sample Preparation, Standards and chemicals, LC/MS/MS, LC/HRMS, LC/MS, LC/TOF

Instrumentation

Consumables, Sample Preparation, Standards and chemicals, LC/MS/MS, LC/HRMS, LC/MS, LC/TOF

Manufacturer

Waters

Industries

Pharma & Biopharma

Evaluating IonHance Hexafluoroisopropanol (HFIP) for Enhanced LC-MS Oligonucleotide Analysis

Applications

| 2024 | Waters

Standards and chemicals, LC/MS

Instrumentation

Standards and chemicals, LC/MS

Manufacturer

Waters

Industries

Pharma & Biopharma

Improved Sensitivity for Trifluoroacetic Acid Gradients on the Alliance™ iS HPLC Systems

Applications

| 2024 | Waters

HPLC

Instrumentation

HPLC

Manufacturer

Waters

Industries

Pharma & Biopharma

Automatic Optimization of Gradient Conditions by AI Algorithm on Synthetic Peptide and Impurities

Applications

| 2024 | Shimadzu

Software, LC/MS, LC/SQ

Instrumentation

Software, LC/MS, LC/SQ

Manufacturer

Shimadzu

Industries

Pharma & Biopharma

Top-Down CDR Sequencing of Native Intact mAbs Through Deconvolution of HC+LC Mixture Spectra

Posters

| 2024 | Agilent Technologies (ASMS)

LC/HRMS, LC/MS, LC/MS/MS, LC/TOF

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/TOF

Manufacturer

Agilent Technologies

Industries

Pharma & Biopharma

Trace-level Estimation of N-Nitroso Isavuconazonium Sulphate in Isavuconazonium Sulphate API Using Nominal Mass LC/MS

Posters

| 2024 | Agilent Technologies (ASMS)

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Agilent Technologies

Industries

Pharma & Biopharma

Sensitive and Selective Quantitation of N- Nitroso Dabigatran Etexilate Impurity in Dabigatran Etexilate API using the Agilent 6495C LC/TQ

Posters

| 2024 | Agilent Technologies (ASMS)

LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Agilent Technologies

Industries

Pharma & Biopharma