Applications focused on LC/HRMS - page 58

Extending the Capabilities of the BioAccord LC-MS System with a streamlined workflow for compliant-ready Multi-Attribute Method (MAM)

Applications

| 2020 | Waters

LC/TOF, LC/HRMS, LC/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS

Manufacturer

Waters

Industries

Pharma & Biopharma, Clinical Research

Developing a Quantitative Surrogate Peptide Assay – Peptide mapping through MRM Optimization for Measuring Dulaglutide in a Rat PK Study

Applications

| 2020 | Waters

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QQQ

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC/QQQ

Manufacturer

Waters

Industries

Proteomics , Clinical Research

Optimizing LC-MS Separations of mAbs using a BioResolve SCX mAb Column and IonHance CX-MS pH Concentrates

Applications

| 2020 | Waters

HPLC, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

HPLC, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Waters

Industries

Clinical Research

High-resolution accurate-mass liquid chromatography mass spectrometry (HRAM LC-MS) methodology for the determination and quantitation of nitrosamine impurities in drug products

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Increasing throughput of native SEC-MS in biopharmaceutical development using a tandem UHPLC setup

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, GPC/SEC

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Fast and accurate quantitation of intact IGF-1 from serum by HRAM LC-MS for clinical research

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Clinical Research

Monoclonal antibody mass confirmation using intact protein deconvolution for a compliance-ready manufacturing environment

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

N-Linked Glycans Analysis of Monoclonal Antibodies, Biosimilars, and Glycoproteins with High Resolution Mass Spectrometry and Fluorescence Detection using Restek’s Raptor Polar X Column and Protein Metrics’ Software Suite

Applications

| 2020 | Shimadzu

HPLC, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

HPLC, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Shimadzu

Industries

Pharma & Biopharma

Protein Clipping Variant Analysis of Vedolizumab using dedicated workflows in BioPharma Compass

Applications

| 2020 | Bruker

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Bruker

Industries

Pharma & Biopharma

Complete de novo sequencing of a human immunoglobulin G using multiple enzyme digests and LC-ESI-QTOF-MS/MS analysis

Applications

| 2020 | Bruker

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Instrumentation

LC/TOF, LC/HRMS, LC/MS, LC/MS/MS

Manufacturer

Agilent Technologies, Bruker

Industries

Clinical Research