Applications focused on LC/Orbitrap - page 4

Optimized one-pot single-cell proteomics workflow

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics

Deeper proteome coverage and faster throughput for low input samples on the Thermo Scientific Orbitrap Astral mass spectrometer

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics

Highly sensitive and robust LC-HRAM-MS method for simultaneous quantitation of sixteen nitrosamines in multiple drug products

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Improved and universal inline electrochemical reduction and subunits LC-MS analysis of multiple classes of monoclonal antibodies

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Coupling ion exchange chromatography with mass spectrometry to characterize charge heterogeneity of mAbs under near-native conditions using a ProPac 3R SCX column

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS/MS, LC/MS, LC/Orbitrap, LC columns, Consumables
Instrumentation
LC/HRMS, LC/MS/MS, LC/MS, LC/Orbitrap, LC columns, Consumables
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Development of a systematic approach for improving tryptic digestion, recovery and chromatographic performance for mAb analysis

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Efficient and sensitive peptide mapping approach by μPAC columns with ultralow sample loading

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC columns, Consumables
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, LC columns, Consumables
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics

Sensitive quantitation of antisense oligonucleotides in plasma using high-resolution, accurate-mass (HRAM) mass spectrometry

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma

Characterization of adeno-associated viral proteins proteoforms using a top-down MS approach on a UHPLC-Orbitrap Ascend Tribrid mass spectrometer

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma, Proteomics

Confident and sensitive profiling of lipid nanoparticle raw materials and impurity identification using a LC/CAD/HRAM-MS method with inverse gradient

Applications
| 2023 | Thermo Fisher Scientific
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Other projects
GCMS
ICPMS
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