Applications focused on GPC/SEC from Thermo Fisher Scientific - page 1

Charge variant analysis of cysteine-linked antibody-drug conjugates using an online multiple heart-cut 2D- SCX-SEC-LC HRAM MS approach

Applications

| 2025 | Thermo Fisher Scientific

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC, 2D-LC

Instrumentation

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC, 2D-LC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Monitoring of multiple quality attributes of intact monoclonal antibodies from bioreactors by switchable 2D-LC-MS

Applications

| 2024 | Thermo Fisher Scientific

GPC/SEC, 2D-LC, LC/MS, LC/Orbitrap, LC/HRMS, LC/MS/MS

Instrumentation

GPC/SEC, 2D-LC, LC/MS, LC/Orbitrap, LC/HRMS, LC/MS/MS

Manufacturer

Thermo Fisher Scientific

Industries

Proteomics

Size-exclusion chromatography of adeno-associated viruses with the SurePac Bio 550 SEC MDi column

Applications

| 2024 | Thermo Fisher Scientific

Consumables, LC columns, GPC/SEC

Instrumentation

Consumables, LC columns, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Size exclusion chromatography with fluorescence detection to determine AAV titers following downstream processing

Applications

| 2022 | Thermo Fisher Scientific

GPC/SEC

Instrumentation

GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Increasing throughput of native SEC-MS in biopharmaceutical development using a tandem UHPLC setup

Applications

| 2020 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, GPC/SEC

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Simultaneous analysis of monoclonal antibodies using a novel dual-channel UHPLC instrument and orthogonal chromatography

Applications

| 2018 | Thermo Fisher Scientific

HPLC, GPC/SEC

Instrumentation

HPLC, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Lifetime stability of size exclusion chromatography columns for protein aggregate analysis

Applications

| 2017 | Thermo Fisher Scientific

Consumables, LC columns, GPC/SEC

Instrumentation

Consumables, LC columns, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

Robust and reproducible peptide mapping and intact mass analysis workflows on a single instrument platform

Applications

| 2017 | Thermo Fisher Scientific

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, GPC/SEC

Instrumentation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

A universal chromatography method for aggregate analysis of monoclonal antibodies

Applications

| 2016 | Thermo Fisher Scientific

Consumables, LC columns, GPC/SEC

Instrumentation

Consumables, LC columns, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma

The importance of correct UHPLC instrument setup for protein aggregate analysis by size-exclusion chromatography

Applications

| 2016 | Thermo Fisher Scientific

Consumables, LC columns, GPC/SEC

Instrumentation

Consumables, LC columns, GPC/SEC

Manufacturer

Thermo Fisher Scientific

Industries

Pharma & Biopharma