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Comprehending COVID-19: LC-MS/MS Analysis of Small Molecule Anti-Viral and Anti-Inflammatory Drugs in Plasma in Clinical Research

 

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ALC-5ENCD58 COVID-19 Stable isotope-labeled Method for multiple COVID-19 drugs analysis by LC-MS/MS 04 MS Conditions HPLC Conditions ℃ ℃ ℃ ℃ Sample preparation ° Table 1: Gradient program Table 2: MRM parameters Molecules Favipiravir GS 441524 Remdesivir Hydroxychloroquine Ref. Transitions…
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desethylchloroquine, desethylchloroquinefavipiravir, favipiravirlopinavir, lopinavirratio, ratioremdesivir, remdesivirritonavir, ritonavirhydroxychloroquine, hydroxychloroquinechloroquine, chloroquinearea, areaazithromycin, azithromycintransitions, transitionsdeviation, deviationaverage, averageconcentrations, concentrationsmolecules
Application Note No. 76 Development of an Assay for the COVID-19 Drug Remdesivir- Toward Proper Remdesivir Use in Patients with Pre-Existing Conditions‐ Atsushi Yonezawa 1, Eishi Imoto2, Yoshihiro Hayakawa2 Pharmaceutical Pharmaceuticals  Abstract This article establishes a mass spectrometer-based analytical…
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Application Note AN959 Sample Preparation Method for Determination of GS-441524 | Page 1 Sample Preparation Method for Determination of GS-441524 (Remdesivir Metabolite) in Plasma Using ISOLUTE ENV+ SPE Columns ® Sample Preparation Procedure Format Format ISOLUTE ENV+ 50 mg/ 1…
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Application Note Comprehending COVID-19: Mixed-Mode Chromatography for Ion Pairing Free LCMS of Remdesivir and Remdesivir Triphosphate Bonnie A. Alden, Peter Christensen, Dominic Foley, Lisa J. Calton, Simon Barnes, Giovanni Gallo, Matthew A. Lauber Waters Corporation Save 15% off on Columns,…
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