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High Throughput Screening and Characterization of Bispecifics Using Native Ion Mobility Mass Spectrometry

Posters | 2016 | Agilent TechnologiesInstrumentation
Ion Mobility, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Industries
Pharma & Biopharma
Manufacturer
Agilent Technologies
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CUSTOMER APPLICATION NOTE 73898 Seamless LC-MS method transfer in a biopharmaceutical development laboratory Authors: Dan Bach Kristensen1, Trine Meiborg Sloth1, Martin Ørgaard1, Pernille Foged Jensen1, Krisztina Radi2 Symphogen, Ballerup, Denmark 1 Thermo Fisher Scientific, Hemel Hempstead, UK 2 Keywords: Native…
Key words
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APPLICATION BRIEF 73554 Sensitive profiling of IgG1 monoclonal antibody variants under native conditions Authors: Sara Carillo and Jonathan Bones NIBRT – The National Institute for Bioprocessing Research and Training, Dublin, Ireland [email protected] Keywords: Monoclonal antibody, native MS, mass spectrometry, biopharma,…
Key words
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Application Note Biopharma Comprehensive Approaches to Higher-Order Structure of Intact Proteins by Native Mass Spectrometry Authors Caroline S. Chu, Patrick D. Perkins, Christian Klein, and Andrew Gieschen Agilent Technologies, Inc. Abstract This application note presents different approaches to native mass…
Key words
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Application Note Pharma & Biopharma Sensitive Native Mass Spectrometry of Macromolecules Using Standard Flow LC/MS Author David L. Wong Agilent Technologies, Inc. Abstract Native mass spectrometry can be used for a variety of protein-based applications, such as protein-protein interaction, protein-ligand…
Key words
native, nativeprotein, proteincounts, countsintact, intactdeconvoluted, deconvolutedamu, amumyoglobin, myoglobinmass, massapomyoglobin, apomyoglobincharge, chargecomplexes, complexesheme, hemeholomyoglobin, holomyoglobintetramer, tetramerdenatured
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