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Rapid Qualitative Analysis and Absolute Quantification of Plasma Proteins Using SONAR with Biognosys PQ500 for Proteomic Clinical Research Studies

 

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[ TECHNOLOGY BRIEF ] Analysis of Plasma Proteome for a Respiratory Disease Cohort Using SONAR on a SYNAPT XS Mass Spectrometer Christopher Hughes, 1 Lee Gethings,1 Joanne Ballantyne,1 and Robert Plumb 2 1 Micromass UK Limited, Wilmslow, Cheshire, UK; 2…
Key words
sonar, sonarsynapt, synaptbrief, briefplatform, platformprogenesis, progenesiscohort, cohortrespiratory, respiratorybpi, bpispecificity, specificitydata, datadia, diatechnology, technologythlapysdelr, thlapysdelrwcavseheatk, wcavseheatkplasma
[ TECHNOLOGY BRIEF ] Rapid Proteomic Analysis Using 1 mm Scale Chromatography, Providing the Required Throughput for Large Cohort Studies Sarah Lennon,¹ Christopher J. Hughes,¹ Robert S. Plumb,² and Lee A. Gethings¹ ¹Waters Corporation, Wilmslow, UK; ²Waters Corporation, Milford, MA,…
Key words
synapt, synaptnanoease, nanoeaseirt, irtuplc, uplcacquity, acquitybrief, briefcohort, cohortshown, shownpeptide, peptideplasma, plasmachromatography, chromatographylflqfgaqgspflk, lflqfgaqgspflkpancreatectomy, pancreatectomyidentifications, identificationsclass
A MULTI-OMICS APPROACH TO INVESTIGATE THE PLASMA PROTEOME AND DETERMINE THE MECHANISITIC PROCESSES INVOLVED IN DIFFERENT RESPIRATORY DISEASE CONDITIONS ThP 127 Christopher J. Hughes, Adam King and Lee A. Gethings Waters Corporation, Wilmslow, UK INTRODUCTION RESULTS Chronic obstructive pulmonary disease…
Key words
copd, copdproteomics, proteomicsasthma, asthmapathway, pathwaylipidomics, lipidomicslipoprotein, lipoproteinscan, scandisease, diseasemetabolomics, metabolomicsplasma, plasmaelevated, elevatedlabelled, labelledemphysema, emphysemamechanisitic, mechanisiticbronchitis
[ APPLICATION NOTE ] A Comparative Qualitative and Quantitative Assessment of SONAR for High-Throughput Proteomic Applications Christopher Hughes, Lee A. Gethings, Robert Plumb, and James I. Langridge Waters Corporation, Wilmslow, United Kingdom APPLICATION BENEFITS INTRODUCTION Qualitative improvements with increased The…
Key words
sonar, sonarproteomic, proteomicswath, swathcomparative, comparativeprotein, proteinqualitative, qualitativeidentifications, identificationsassessment, assessmentquantitative, quantitativenanoease, nanoeasedia, diathroughput, throughputquadrupole, quadrupolestepped, steppedacquisition
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