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Gradient Method Scaling for Life Cycle Management of a USPImpurities MethodAmanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■The Waters™ Columns Calculator enablesPharmaceutical companies often follow compendial high performanceusers to geometrically scale methodsliquid chromatography (HPLC)...
Key words
quetiapine, quetiapinescaling, scalingacquity, acquityuplc, uplchplc, hplcfumarate, fumarateimpurities, impuritiesmethod, methoduhplc, uhplcusp, uspgradient, gradientarc, arcalliance, alliancecolumns, columnsscaled
Scaling USP Methods to Smaller Particle Columnson the Alliance HPLC SystemAmanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■INTRODUCTIONReduce run time and solventThe continual development and modernization of pharmaceuticalconsumption by scaling an isocraticprocedures helps to...
Key words
alliance, alliancehplc, hplcscaling, scalingquetiapine, quetiapinesmaller, smallerscaled, scaledparticle, particleuhplc, uhplcusp, uspcolumns, columnscolumn, columnisocratic, isocraticsystem, systemmethod, methodmethods
Scaling of a USP Assay for Quetiapine Fumarate AcrossDifferent Liquid Chromatographic SystemsAmanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■The Waters Column Calculator enablesUsers of compendial chromatographic procedures increasingly look tousers to scale a method...
Key words
usp, uspquetiapine, quetiapinefumarate, fumaratescaling, scalingassay, assayacquity, acquitysystem, systemalliance, allianceuplc, uplchplc, hplcacross, acrossmethod, methodarc, arcsuitability, suitabilitycompendial
Alliance Carryover Performance Part 1: Carryover Improvement AchievedThrough Instrument Design Changes for the Alliance HPLC SystemAmanda B. Dlugasch, Jennifer Simeone, Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONImproved carryover performance forSample carryover is a common problem for analytical laboratories and...
Key words
carryover, carryoveralliance, alliancecoumarin, coumarinhplc, hplccaffeine, caffeinechlorhexidine, chlorhexidinefumarate, fumaratequetiapine, quetiapineneedle, needledesign, designseal, sealnormal, normalsolution, solutionpack, packsystem
 

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Gradient Method Scaling for Life Cycle Management of a USPImpurities MethodAmanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■The Waters™ Columns Calculator enablesPharmaceutical companies often follow compendial high performanceusers to geometrically scale methodsliquid chromatography (HPLC)...
Key words
quetiapine, quetiapinescaling, scalingacquity, acquityuplc, uplchplc, hplcfumarate, fumarateimpurities, impuritiesmethod, methoduhplc, uhplcusp, uspgradient, gradientarc, arcalliance, alliancecolumns, columnsscaled
Scaling USP Methods to Smaller Particle Columnson the Alliance HPLC SystemAmanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■INTRODUCTIONReduce run time and solventThe continual development and modernization of pharmaceuticalconsumption by scaling an isocraticprocedures helps to...
Key words
alliance, alliancehplc, hplcscaling, scalingquetiapine, quetiapinesmaller, smallerscaled, scaledparticle, particleuhplc, uhplcusp, uspcolumns, columnscolumn, columnisocratic, isocraticsystem, systemmethod, methodmethods
Scaling of a USP Assay for Quetiapine Fumarate AcrossDifferent Liquid Chromatographic SystemsAmanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■The Waters Column Calculator enablesUsers of compendial chromatographic procedures increasingly look tousers to scale a method...
Key words
usp, uspquetiapine, quetiapinefumarate, fumaratescaling, scalingassay, assayacquity, acquitysystem, systemalliance, allianceuplc, uplchplc, hplcacross, acrossmethod, methodarc, arcsuitability, suitabilitycompendial
Alliance Carryover Performance Part 1: Carryover Improvement AchievedThrough Instrument Design Changes for the Alliance HPLC SystemAmanda B. Dlugasch, Jennifer Simeone, Patricia R. McConvilleWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONImproved carryover performance forSample carryover is a common problem for analytical laboratories and...
Key words
carryover, carryoveralliance, alliancecoumarin, coumarinhplc, hplccaffeine, caffeinechlorhexidine, chlorhexidinefumarate, fumaratequetiapine, quetiapineneedle, needledesign, designseal, sealnormal, normalsolution, solutionpack, packsystem
 

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