Charge Variant Analysis of Infliximab on the Alliance, ACQUITY Arc Bio, and ACQUITY UPLC H-Class Bio Liquid Chromatography Systems Using a Quaternary pH Gradient | LabRulez LCMS
 

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Auto•Blend Plus Technology for Ion-Exchange ChromatographyMethod Development and Robustness TestingHua Yang, Bill Warren, and Stephan KozaWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAuto•Blend™ Plus TechnologyIon-exchange chromatography (IEX) is widely used for the charge-variantfacilitated IEX method developmentanalysis of protein biotherapeutics. Its ability to...
Key words
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Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2DPart 2 of 3: Rendering a Viable Interface for IEX with ESI-MS AnalysisRobert Birdsall, Sean M. McCarthy, and Weibin ChenWaters Corporation, Milford, MA, USAA P P L I C AT I O...
Key words
acquity, acquityuplc, uplciex, iexproductivity, productivitytherapeutic, therapeuticdesalting, desaltingbio, biofractionation, fractionationbiotherapeutics, biotherapeuticsrenders, rendersheart, heartcharacterization, characterizationefficient, efficientcut, cutmanager
Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2DPart 1 of 3: On-line Desalting of Biotherapeutic Samplesfor Increased ProductivityRobert Birdsall, Sean M. McCarthy, and Weibin ChenWaters Corporation, Milford, MA, USAA P P L I C AT I O N B...
Key words
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Developing Robust and Efficient IEX Methods for Charge Variant Analysis ofBiotherapeutics Using ACQUITY UPLC H-Class System and Auto • Blend PlusRobert Birdsall, Thomas Wheat, and Weibin ChenWaters Corporation, Milford, MA, USAA P P L I C AT I O N...
Key words
blend, blendiex, iexauto, autorobust, robustplus, pluscharge, chargevariant, variantbiotherapeutics, biotherapeuticsdevelopment, developmentdeveloping, developingefficient, efficientuplc, uplcbuffer, bufferacquity, acquityclass
 

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Auto•Blend Plus Technology for Ion-Exchange ChromatographyMethod Development and Robustness TestingHua Yang, Bill Warren, and Stephan KozaWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAuto•Blend™ Plus TechnologyIon-exchange chromatography (IEX) is widely used for the charge-variantfacilitated IEX method developmentanalysis of protein biotherapeutics. Its ability to...
Key words
blend, blendauto, autoplus, plussalt, saltmethod, methodvariant, variantrobustness, robustnesstechnology, technologyinitial, initialcharge, chargegradient, gradientexchange, exchangedevelopment, developmentminutes, minutestesting
Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2DPart 2 of 3: Rendering a Viable Interface for IEX with ESI-MS AnalysisRobert Birdsall, Sean M. McCarthy, and Weibin ChenWaters Corporation, Milford, MA, USAA P P L I C AT I O...
Key words
acquity, acquityuplc, uplciex, iexproductivity, productivitytherapeutic, therapeuticdesalting, desaltingbio, biofractionation, fractionationbiotherapeutics, biotherapeuticsrenders, rendersheart, heartcharacterization, characterizationefficient, efficientcut, cutmanager
Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2DPart 1 of 3: On-line Desalting of Biotherapeutic Samplesfor Increased ProductivityRobert Birdsall, Sean M. McCarthy, and Weibin ChenWaters Corporation, Milford, MA, USAA P P L I C AT I O N B...
Key words
uplc, uplcacquity, acquitydesalting, desaltingheart, heartiex, iexcut, cutfractionation, fractionationdesalted, desaltedbio, bioinfliximab, infliximabmanager, managersimulated, simulatedcharacterization, characterizationbiotherapeutic, biotherapeuticoften
Developing Robust and Efficient IEX Methods for Charge Variant Analysis ofBiotherapeutics Using ACQUITY UPLC H-Class System and Auto • Blend PlusRobert Birdsall, Thomas Wheat, and Weibin ChenWaters Corporation, Milford, MA, USAA P P L I C AT I O N...
Key words
blend, blendiex, iexauto, autorobust, robustplus, pluscharge, chargevariant, variantbiotherapeutics, biotherapeuticsdevelopment, developmentdeveloping, developingefficient, efficientuplc, uplcbuffer, bufferacquity, acquityclass
 

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