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Biotherapeutic Peptide Mass Confirmation and Impurity Profiling on a SmartMS Enabled BioAccord LC-MS System

 

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[ APPLICATION NOTE ] Synthetic Peptide Characterization and Impurity Profiling Using a Compliance-Ready LC-HRMS Workflow Nilini Ranbaduge and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ A compliance-ready solution for peptide Peptide-based therapeutics are alpha amino…
Key words
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[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…
Key words
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[ TECHNOLOGY BRIEF ] Routine Peptide Mapping Analysis using the BioAccord System Nilini Ranbaduge, Henry Shion, and Ying Qing Yu Waters Corporation, Milford, MA, USA SmartMS-enabled BioAccord System improves the operational efficiency for routine peptide mapping analysis. GOAL Demonstrate how…
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A WORKFLOW DRIVEN PLATFORM SOLUTION FOR MAM-BASED CRTICAL QUALITY ATTRIBUTE MONITORING OF BIOTHERAPEUTICS IN PROCESS DEVELOPMENT AND QC Nilini S Ranbaduge, Ying Qing, Min Du, Weibin Chen Waters Corporation, 34 Maple Street, Milford, MA 01757, USA INTRODUCTION Biotherapeutics undergo rigorous…
Key words
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