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Improving Drug Metabolite Identification in Biofluids with the ACQUITY PREMIER and Hybrid Organic Surface Technology: Increased Sensitivity and Reproducibility

 

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MaxPeak Premier Columns Small Molecule Application Notebook CONTENTS Introduction Non-Specific Adsorption: Unwanted Interactions................................................................................... 3 How Do Scientists Solve This Problem Today?......................................................................................... 4 Precision Chemistry for Particles and Surfaces........................................................................................ 5 Fundamentals Waters™ Premier Standards to Investigate the Inertness of Chromatographic Systems....................................................................................................................................7…
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Application Note Advantages of using ACQUITY PREMIER System and Columns with MaxPeak HPS Technology for Bioanalysis of Gefitinib – an EGFR Inhibitor Nikunj Tanna, Robert S. Plumb Waters Corporation This is an Application Brief and does not contain a detailed…
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[ WHITE PAPER ] Low Adsorption UPLC Systems and Columns Based on MaxPeak High Performance Surfaces: The ACQUITY Premier Solution T. H. Walter, M. Trudeau, J. Simeone, P. Rainville, A. V. Patel, M. A. Lauber, J. Kellett, M. DeLano, K.…
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Application Note Rapid High Sensitivity LC-MS/MS Bioanalytical Method for the Simultaneous Quantification of Gefitinib Based PROTACs – 3 and Gefitinib in Rat Plasma to Support Discovery DMPK Studies Robert S. Plumb Waters Corporation This is an Application Brief and does…
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