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Reducing Sample Volume and Increasing Sensitivity for the Quantification of Human Insulin and 5 Analogs in Human Plasma Using ionKey/MS

 

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[ APPLICATION NOTE ] Simultaneous Analysis of Intact Human Insulin and Five Analogs in Human Plasma Using µElution SPE and a CORTECS UPLC Column Erin E. Chambers and Kenneth J. Fountain Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■…
Key words
insulin, insulinhuman, humandetemir, detemirglulisine, glulisinelispro, lisproglargine, glargineanalogs, analogsaspart, aspartchain, chainintact, intactplasma, plasmasimultaneous, simultaneousfive, fiveinsulins, insulinsmean
[ TECHNOLOGY BRIEF ] Increasing Throughput for the Analysis of Human Insulin and Related Biotherapeutic Analogs using the ionKey/MS System Michael Donegan, James Murphy, and Erin Chambers Waters Corporation, Milford, MA, USA The ionKey/MS System enables the flexibility to modulate…
Key words
insulin, insulinmicroflow, microflowionkey, ionkeyanalogs, analogsglulisine, glulisinehuman, humanbrief, briefdetemir, detemiraspart, aspartsystem, systemlispro, lisproglargine, glarginemodulate, modulatethroughput, throughputsensitivity
[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…
Key words
ionkey, ionkeypeptide, peptideplasma, plasmaquantification, quantificationhuman, humanarea, areainsulin, insulinxevo, xevoprotein, proteinuplc, uplcpeptides, peptidesmrm, mrmproteinworks, proteinworksantibody, antibodyusing
[ ion key / MS ] APPLICATION COMPENDIUM Dear Colleague, The 2014 introduction of the ionKey/MS System was a turning point for LC-MS. The promise of increased levels of sensitivity from smaller sample sizes was finally a reality. We were…
Key words
ionkey, ionkeyikey, ikeyuplc, uplcsystem, systemplasma, plasmasensitivity, sensitivityhuman, humanion, ionusing, usingmobility, mobilityarea, areadevice, deviceassay, assayseparation, separationquantification
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