Application of Agilent AdvanceBio Desalting-RP Cartridges for LC/MS Analysis of mAbs
Applications | 2016 | Agilent TechnologiesInstrumentation
Consumables, LC/MS, LC columns, 2D-LC
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsdesalting, advancebio, counts, dimension, cartridge, heart, waste, mabs, cutting, agilent, iex, mass, deconvoluted, profile, second, salts, monoclonal, room, cartridges, pump, first, min, charge, flow, consistent, nacl, amu, underpins, time, dimensional, timothy, koen, effectively, salt, removed, injection, tic, samples, sandra, characterization, application, separated, used, effective, spectrum, protein, glycoform, quantification, note, ion
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ADVANCE YOUR CONFIDENCE FOR BIOTHERAPEUTICS Agilent AdvanceBio Desalting-RP cartridges Perform reversed-phase removal of salt ions—online—before MS detection Characterizing complex proteins—including monoclonal antibodies—requires multiple techniques, such as affinity, ion exchange, and size exclusion chromatography. However, the mobile phases used for these…
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