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Enantiomeric Separation of the Active Metabolite of Risperidone and its Application for Monitoring Metabolic Stability using UPC2/MS/MS

 

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Enantiomeric Separation of Warfarin and Propranolol and their Associated Hydroxylated Metabolites using UPC2-MS/MS Jennifer Simeone and Paul Rainville G OA L UltraPerformance Convergence Chromatography™ To illustrate the effectiveness of convergence chromatography for the separation of compounds with chiral centers. Adding…
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Investigating the Chiral Metabolism of an Achiral Drug Using Agilent SFC‑MS/MS Technology Application Note Pharma Discovery Authors Abstract Siji Joseph A robust SFC-MS/MS method was developed for the quantification of achiral Agilent Technologies, Inc. risperidone and its enantiomeric hydroxy metabolite.…
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AGROCHEMICAL SOLUTIONS APPLICATION NOTEBOOK Accelerate Synthesis, Purification, and Formulation AGROCHEMICAL SOLUTIONS APPLICATION NOTEBOOK Developing next-generation crop protection solutions To accelerate the development of highly effective, environmentally friendly agrochemicals, laboratories must perform analyses that generate more information, are completed more rapidly…
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Separation of Diastereomeric Chiral Metabolites Using UPC 2 MS/MS Chester L. Bowen,1 Hermes Licea-Perez,1 Paul D. Rainville,2 Tom DiPillipo,2 Denise Heyburn,2 Robert S. Plumb,2 and Christopher Evans1 1 Bioanalytical Sciences and Toxicokinetics, PTS DMPK, GlaxoSmithKline, King of Prussia, PA, USA…
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