Agilent InfinityLab Supplies for the 1260 Infinity II Preparative LC System - Quick Reference Guide

Significance of the topic

Preparative liquid chromatography (LC) is a cornerstone technique for isolating and purifying target compounds in pharmaceuticals, biotechnology, and chemical manufacturing. High‐quality consumables and preventive maintenance (PM) kits are critical for maintaining system performance, minimizing downtime, and ensuring consistent purification yields.

Objectives and overview of the guide

This quick reference guide compiles the most frequently ordered supplies and PM parts for the Agilent 1260 Infinity II Preparative LC System. It organizes components by instrument module and provides part numbers and PM frequency to streamline ordering and inventory management.

Methodology and instrumentation

The manufacturer‐driven methodology involves identifying key wear parts and maintenance kits required at regular intervals. Items are grouped under system modules to simplify selection during PM procedures or consumable replenishment.

Used instrumentation

• 1260 Infinity II Preparative Binary Pump (G7161A)
• 1260 Infinity II Preparative Autosampler (G7157A)
• Manual Preparative Injector (G1328D)
• Evaporative Light Scattering Detector (G4260B)
• MS Flow Modulator (G7170B)
• Delay Coil Organizer (G9324A)
• Preparative Fraction Collector (G1364E)
• 1260 Infinity II Diode Array Detector (G7115A) and Variable Wavelength Detector (G7114A)
• Valve‐Based Preparative Fraction Collector (G7166A)
• Column Organizer (G9328A) and clustering valves (G9322A)
• Miscellaneous tubing, fittings, solvent bottles, and vials

Main results and discussion

The guide lists critical components for each module:

• Pump seals, pistons, filters, and capillary kits for varying flow rates;
• Autosampler needles, rotor seals, sample loops, and vial trays;
• Injector rotor/stator seals, syringes, and sample loops of different materials;
• Detector lamps, flow cells, and splitter kits;
• Fraction collector tubing kits and tray configurations;
• Valve stators, rotors, and selector capillary kits;
• Consumables such as solvent bottles, ESD‐safe tubing, and screw‐cap vials.

Preventive maintenance kits for each module are highlighted to facilitate on‐time part replacement.

Benefits and practical applications

Using genuine Agilent supplies:

• Ensures reproducible flow and pressure stability;
• Reduces risk of contamination or system leaks;
• Optimizes purification throughput and product purity;
• Supports compliance with quality standards (ISO 9001).

Future trends and potentials

Emerging capabilities include integration of RFID‐enabled consumables for automated inventory tracking, predictive maintenance alerts via instrument software, and advanced materials for extended part lifetimes. Connectivity with laboratory information management systems (LIMS) will further streamline ordering and maintenance workflows.

Conclusion

This reference guide provides a structured overview of essential consumables and PM kits for the 1260 Infinity II Preparative LC System. Adopting these genuine parts supports reliable system performance and efficient lab operations.

Reference

Agilent Technologies. Quick Reference Guide: InfinityLab Supplies for the 1260 Infinity II Preparative LC System. October 2018.