High Resolution and Rapid Peptide Mapping of Monoclonal Antibody Using an Agilent 1290 Infi nity UHPLC and an Agilent 6550 iFunnel Q-TOF LC/MS System
Applications | 2013 | Agilent Technologies Instrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordspeptide, mapping, counts, superficially, sequence, jetstream, acquisition, identified, monoclonal, antibody, efficiency, time, ptms, agilent, column, charge, flow, martosella, advancebio, map, resolution, sequences, added, min, porous, resolving, zhu, coverage, mab, maximize, sheath, confident, tang, ning, novel, gas, peptides, alex, report, drying, advancement, biologic, second, interpreted, sample, post, james, workflow, generated, system
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Agilent-NISTmAbPeptide MappingAgilent BioHPLC ColumnsApplication CompendiumContentsAgilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted fromNISTmAb RM 8671 batch. Quality control (QC) testing is performed usingAgilent LC-MS system. QC batch release test includes aggregate profile, chargevariants and intact mass information. A certificate of analysis...
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An Integrated Workflow for PeptideMapping of Monoclonal AntibodiesApplication NoteBiotherapeutics and BiosimilarsAuthorsIntroductionDavid L. WongMonoclonal antibodies (mAbs) represent one of the fastest growing classes of drugsin the pharmaceutical industry. As a protein drug, the manufacturing of an mAb frominitial expression to commercialization...
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