High Resolution and Rapid Peptide Mapping of Monoclonal Antibody Using an Agilent 1290 Infi nity UHPLC and an Agilent 6550 iFunnel Q-TOF LC/MS SystemApplications | 2013 | Agilent TechnologiesInstrumentationLC/TOF, LC/HRMS, LC/MS, LC/MS/MSIndustriesPharma & BiopharmaManufacturerAgilent TechnologiesKey wordspeptide, mapping, counts, superficially, sequence, jetstream, acquisition, identified, monoclonal, antibody, efficiency, ptms, time, agilent, charge, column, flow, martosella, advancebio, map, resolution, added, sequences, min, coverage, porous, resolving, zhu, mab, maximize, sheath, tang, ning, confident, peptides, novel, gas, report, alex, advancement, second, biologic, drying, interpreted, sample, generated, james, post, unique, automatically
Similar PDF
BIOPHARMA WORKFLOW SOLUTIONS - Drug Development and Quality Control
2017|Agilent Technologies|Brochures and specifications
Drug Development and Quality ControlBIOPHARMA WORKFLOW SOLUTIONSHOW AGILENT HELPS RESOLVECOMPLEX ANALYTICAL CHALLENGES++COMPLEX CHALLENGESThe work you do is extraordinarily complicated and labor-intensive; we can helpWe know you have a lot of samples to analyze, and we know what an understatement that...
Key words
glycan, glycanmapping, mappingpeptide, peptideprotein, proteinwalkup, walkuppump, pumpagilent, agilentmab, mabantibody, antibodyintact, intactanalysis, analysismass, masscapillary, capillaryregenerate, regenerateptms
An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies
2017|Agilent Technologies|Applications
An Integrated Workflow for PeptideMapping of Monoclonal AntibodiesApplication NoteBiotherapeutics and BiosimilarsAuthorsIntroductionDavid L. WongMonoclonal antibodies (mAbs) represent one of the fastest growing classes of drugsin the pharmaceutical industry. As a protein drug, the manufacturing of an mAb frominitial expression to commercialization...
Key words
peptide, peptidemab, mabmapping, mappingcounts, countsassaymap, assaymapsgtasvvcllnnfypr, sgtasvvcllnnfypracquisition, acquisitionworkflow, workflowdigestion, digestioncharge, chargesequence, sequencewere, werenist, nistdigested, digesteddiqmtqspstlsasvgdrvtitcsassr
Making Peptide Mapping Routine with the Agilent 6545XT AdvanceBio LC/Q-TOF
2017|Agilent Technologies|Applications
Making Peptide Mapping Routinewith the Agilent 6545XT AdvanceBioLC/Q-TOFApplication NoteAuthorsIntroductionDavid L. WongMonoclonal antibodies (mAbs) comprise a rapidly growing group of protein-basedbiomolecules being researched. Due to the heterogeneous nature of protein drugs,extensive analytical characterization is required.Agilent Technologies, Inc.Santa Clara, CA, USAJing ChenAgilent...
Key words
peptide, peptidemapping, mappingpeptides, peptidesadvancebio, advancebioassaymap, assaymapagilent, agilentbravo, bravonqvsltclvk, nqvsltclvkcharge, chargecounts, countsnative, nativemonoclonal, monoclonalantibody, antibodymass, massbioconfirm
Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System
2017|Agilent Technologies|Applications
Peptide Mapping of Innovator andBiosimilar Monoclonal AntibodyUsing an Agilent 1290 Infinity UHPLCCoupled to an Agilent 6550 iFunnelQ-TOF LC/MS SystemApplication NoteAuthorIntroductionRavindra GudihalMonoclonal antibodies (mAbs) are becoming one of the important classes ofbiomolecules for the treatment of various cancers. Biosimilar mAbs, which...
Key words
peptide, peptideinnovator, innovatorbiosimilar, biosimilardeamidation, deamidationoxidation, oxidationcounts, countsdltmisr, dltmisrmapping, mappingtrypsin, trypsinunmodified, unmodifiedoxi, oxiheight, heightions, ionscharge, chargegfypsdiavewesngqpennyk